Discussion on Treatment of Recurrent Genital Herpes with Zhulingtang： Based on Thought of "Lower Energizer Resembling Drainage"

Ya-qin LI; Qing-ying WANG; Tao-tao SHEN; Meng-xi MA; Si-qi WU; Na LANG

doi:10.13422/j.cnki.syfjx.20220436

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Discussion on Treatment of Recurrent Genital Herpes with Zhulingtang： Based on Thought of "Lower Energizer Resembling Drainage"

更新时间：2022-01-13

- Discussion on Treatment of Recurrent Genital Herpes with Zhulingtang： Based on Thought of "Lower Energizer Resembling Drainage"
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 28, Issue 4, Pages: 240-245(2022)
- 作者机构：
  
  1.中国中医科学院西苑医院，北京 100091
  2.巴音郭楞蒙古自治州人民医院，新疆巴音郭楞蒙古自治州 841000
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20220436
  CLC： R2-0;R285;R33;R26
- Received：25 September 2021，
  
  Published Online：13 December 2021，
  
  Published：20 February 2022
- 稿件说明：
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李亚琴,王清滢,申淘淘等.基于“下焦如渎”探讨猪苓汤治疗复发性生殖器疱疹[J].中国实验方剂学杂志,2022,28(04):240-245.

LI Ya-qin,WANG Qing-ying,SHEN Tao-tao,et al.Discussion on Treatment of Recurrent Genital Herpes with Zhulingtang： Based on Thought of "Lower Energizer Resembling Drainage"[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(04):240-245.
李亚琴,王清滢,申淘淘等.基于“下焦如渎”探讨猪苓汤治疗复发性生殖器疱疹[J].中国实验方剂学杂志,2022,28(04):240-245. DOI： 10.13422/j.cnki.syfjx.20220436.

LI Ya-qin,WANG Qing-ying,SHEN Tao-tao,et al.Discussion on Treatment of Recurrent Genital Herpes with Zhulingtang： Based on Thought of "Lower Energizer Resembling Drainage"[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(04):240-245. DOI： 10.13422/j.cnki.syfjx.20220436.

摘要

复发性生殖器疱疹是感染单纯疱疹病毒导致的一种性传播疾病，主要表现为生殖器及肛门部位皮肤黏膜出现红斑、丘疹、水疱、糜烂及渗出等症状，常伴随灼热疼痛等自觉症状。劳累、发热、饮酒、感染、性行为等为导致其复发的重要因素。在15~49岁人群中，每10人便有超过1人感染2型单纯疱疹病毒。目前尚无彻底清除单纯疱疹病毒，防止其复发的方法，疾病反复发作严重影响患者生活质量及心理健康。中医认为复发性生殖器疱疹发病多与风、湿、热、肝肾阴虚、七情内伤及饮食偏嗜等因素有关，在临床应用过程中显示中医治疗在降低其复发率方面有一定优势。下焦与皮肤疾病密切相关，且“下焦如渎”，与水湿代谢息息相关。复发性生殖器疱疹位处下焦，属下焦疾病范畴，下焦的水液代谢、气机通利与其发生发展密切相关。该文在“下焦如渎”的理论指导下，结合复发性生殖器疱疹之临床特点，探讨其病因病机，认为下焦失畅为其病机。“下焦如渎”，宜因势利导，疏通下焦，治法关键在于“其下者引而竭之”，引邪自下焦去而不伤阴，以通兼补。猪苓汤为《伤寒杂病论》中治疗小便不利、渴欲饮水的经典方剂，其作用机制实为通过疏通下焦而使渴止便利，故选用猪苓汤治疗复发性生殖器疱疹，以期为之提供一种新的理论思路，有助于其临床辨治。

Abstract

Recurrent genital herpes is a sexually transmitted disease induced by herpes simplex virus（HSV）， mainly manifested as erythema， papules， vesicles， erosion， and exudation on the skin and mucosal membranes of the genital and anal area， accompanied by burning pain， or tingling. Factors leading to its recurrence are overworking， fever， alcohol consumption， infection， sexual activity， etc. At least 1 in 10 of the 15-49-year-old population are infected with herpes simplex virus-2. There is currently no available method to completely remove the herpes simplex virus and prevent its recurrence， and recurrence seriously affects the quality of life and psychological health of patients. According to the theory of traditional Chinese medicine （TCM）， the recurrence of genital herpes is mostly related to wind， dampness， heat， yin deficiency of liver and kidney， internal injuries due to emotional disorder， and dietary preference. TCM has advantages in reducing its recurrence rate. The lower energizer is closely related to skin diseases， and "lower energizer resembles drainage". Thus， the lower energizer is closely related to water and damp metabolism. Recurrent genital herpes occurs in the lower energizer and belongs to lower energizer diseases， and the fluid metabolism and qi movement in lower energizer are closely related to the occurrence of the disease. Based on thought of "lower energizer resembling drainage" and the clinical characteristics of recurrent genital herpes， this paper considered malfunction of lower energizer as its pathogenesis. Thus， smoothing the lower energizer according to the prevailing circumstances is particularly important and the treatment principle should be dispersing the pathogen from lower energizer without damaging yin. Zhulingtang （

Treatise on Cold Damage and Miscellaneous Diseases

） cures the difficulty in urination and thirst with desire to drink by smoothing the lower energizer. Thus， Zhulingtang was selected to treat recurrent genital herpes. This study is expected to provide a new idea for its clinical diagnosis and treatment.

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references

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