LI Fuping,FEI Lixian,WANG Xiaowen,et al.Ancient Literature on Qingweisan and Its Modern Clinical Application[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(22):47-57.
LI Fuping,FEI Lixian,WANG Xiaowen,et al.Ancient Literature on Qingweisan and Its Modern Clinical Application[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(22):47-57. DOI: 10.13422/j.cnki.syfjx.20221113.
Ancient Literature on Qingweisan and Its Modern Clinical Application
Qingweisan is one of the classical prescriptions commonly used in the treatment of oral diseases. By means of Bibliometrics, the authors collected the ancient books on Qingweisan and sifted out 411 valid data, involving 116 classics of traditional Chinese medicine. The historical origin, drug composition, indications, principle of composition, dosage,and preparation of Qingweisan were statistically analyzed, and it was found that the prescription originated from the
Treatise on Spleen and Stomach
(《脾胃论》) by LI Dongyuan and is composed of Rehmanniae Radix, Angelica Sinensis, Cortex Moutan, Coptidis Rhizoma and Cimicifugae Rhizoma, with the functions of clearing stomach, purging fire, cooling blood and dispersing depression. And Qingweisan was mainly used to treat toothache, headache, and preference for cold and aversion to heat caused by "excessive heat in yang brightness meridian". There were 352 indications recorded, most of which followed LI Dongyuan's theory and the expanded indications reached 70 kinds. Specifically, toothache (132) was the most, accounting for 22.49% of the total indications, followed by headache (60, 10.22%). In addition, Qingweisan was widely used in modern clinical practice for multiple system diseases, among which oral system (197) was dominant, accounting for 72.69%, followed by skin system (28, 10.33%) and digestive system (27, 9.96%). Although the indications were wide, the pathogenesis always belonged to "upward attack of stomach fire". Through the excavation and statistical analysis of the ancient books on Qingweisan and its modern clinical application, the authors aimed to provide a more scientific reference for the research and application of classical famous prescriptions.
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Related Institution
School of Pharmacy,Key Laboratory of Basic and Application Research of North Medicine,Ministry of Education,Heilongjiang University of Chinese Medicine
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The First Affiliated Hospital of Hunan University of Chinese Medicine