Characteristics of Traditional Chinese Medicine Syndromes in 296 Patients with Urolithiasis

LIU Han; ZHANG Yaosheng

doi:10.13422/j.cnki.syfjx.20230417

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Characteristics of Traditional Chinese Medicine Syndromes in 296 Patients with Urolithiasis

更新时间：2023-04-13

- Characteristics of Traditional Chinese Medicine Syndromes in 296 Patients with Urolithiasis
  增强出版
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 29, Issue 10, Pages: 209-215(2023)
- 作者机构：
  
  北京中医药大学东直门医院，北京 100700
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20230417
  CLC： R284;R285;R289;R287;R22;R2-031;R33;R24
- Published：20 May 2023，
  
  Published Online：14 March 2023，
  
  Received：11 February 2023，
- 稿件说明：
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刘菡,张耀圣.296例尿石症患者中医证候特征[J].中国实验方剂学杂志,2023,29(10):209-215.

LIU Han,ZHANG Yaosheng.Characteristics of Traditional Chinese Medicine Syndromes in 296 Patients with Urolithiasis[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(10):209-215.
刘菡,张耀圣.296例尿石症患者中医证候特征[J].中国实验方剂学杂志,2023,29(10):209-215. DOI： 10.13422/j.cnki.syfjx.20230417.

LIU Han,ZHANG Yaosheng.Characteristics of Traditional Chinese Medicine Syndromes in 296 Patients with Urolithiasis[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(10):209-215. DOI： 10.13422/j.cnki.syfjx.20230417.

摘要

目的

分析尿石症患者的中医证候特征。

方法

制定证候调查表，收集2021年9月至2022年9月就诊的296例尿石症患者的一般资料、四诊信息，统计舌象、脉象、症状体征，通过关联规则分析、因子分析和聚类分析探究证候特点。

结果

①舌象分布中，出现频率在20%以上的单一舌象为白苔、红舌、厚苔、腻苔、黄苔。脉象分布中，出现频率>20%的单一脉象为细脉、弦脉、滑脉、沉脉。出现频率在10%以上的症状体征共27项，腰腹部疼痛及恶心、尿频、血尿、小便不畅等急性发作期特征症状相对较多，其余以寒热、二便和消化类症状较为常见。②14条强关联规则中，5条为阳虚、寒湿类证候表现，4条为阴虚、热证类证候表现，1条为肾虚类证候表现，3条为肾绞痛及伴随症状。③因子分析共提取16个公因子，代表的病位证候要素以脾肾为主，病性证候要素以阴虚、阳虚、湿、热为主，并常见虚实夹杂。聚类分析共获得6类证候，代表的主要证型分别为肾虚湿瘀、气滞热结、阴虚湿热、脾肾阳虚、脾虚湿热、湿热内蕴。

结论

尿石症患者证候表现以寒热、二便、汗出和消化道症状常见，虚证类证候主要为阴虚、阳虚、肾虚、脾虚，实证类证候主要为湿、热，虚实类证候常相兼存在，脾虚是当前尿石症患者除肾虚外的重要病机。

Abstract

Objective

To analyze the characteristics of tradition Chinese medicine (TCM) syndromes in patients with urolithiasis.

Method

A syndrome questionnaire was developed to collect the general data and four diagnosis information on 296 patients with urolithiasis who were treated from September 2021 to September 2022. Tongue images

pulse images

symptoms

and signs were statistically analyzed

and the characteristics of syndrome were explored by association rule analysis

factor analysis

and cluster analysis.

Result

① In the distribution of tongue images

the single tongue images with a frequency of more than 20% were white fur

red tongue

thick fur

greasy fur

and yellow fur. In the distribution pf pulse images

the single pulse with the frequency of more than 20% was fine pulse

string pulse

slippery pulse

and sinking pulse. There were 27 symptoms and signs with a frequency of more than 10%. The characteristic symptoms of acute onset such as lumbar and abdominal pain and nausea

frequent urination

hematuria

and poor urination were relatively common

and other symptoms were chill and fever

defecation

and digestion. ② Among the 14 strong association rules

5 were yang-deficiency and cold-dampness syndromes

4 were yin-deficiency and heat syndromes

1 was kidney-deficiency syndrome

and 3 were renal colic with accompanying symptoms. ③ Sixteen common factors were extracted by factor analysis

and the main elements of the disease location were represented by spleen and kidney. The main elements of disease natures were Yin deficiency

Yang deficiency

dampness

and heat

and often mixed with deficiency-excess in complexity. Six syndromes were obtained by cluster analysis

and the represented syndromes were mainly kidney deficiency and dampness and stasis

Qi stagnation and heat accumulation

Yin deficiency and dampness heat

spleen-kidney Yang deficiency

spleen deficiency and dampness

and dampness-heat accumulation.

Conclusion

The syndrome manifestations of urolithiasis are chill and fever

defecation

sweating

and digestive tract symptoms. The deficiency syndromes are mainly Yin deficiency

Yang deficiency

kidney deficiency

and spleen deficiency. The excess syndromes are mainly wet and heat. The deficiency and excess syndromes often exist simultaneously. The spleen deficiency is the important pathogenesis of urolithiasis besides the kidney deficiency.

关键词

尿石症证候要素证候特征数据挖掘

Keywords

urolithiasissyndrome elementssyndrome characteristicsdata mining

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