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1.辽宁中医药大学,沈阳 110847
2.辽宁中医药大学 附属医院,沈阳 110847
Received:13 October 2022,
Published Online:01 February 2023,
Published:05 August 2023
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张思雨,李晓斌,喻明等.基于肺脾肾“五行相生”理论论治肺癌[J].中国实验方剂学杂志,2023,29(15):172-178.
ZHANG Siyu,LI Xiaobin,YU Ming,et al.Treatment of Lung Cancer Based on Theory of "Generation of Five Elements" of Lung, Spleen, and Kidney[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(15):172-178.
张思雨,李晓斌,喻明等.基于肺脾肾“五行相生”理论论治肺癌[J].中国实验方剂学杂志,2023,29(15):172-178. DOI: 10.13422/j.cnki.syfjx.20230630.
ZHANG Siyu,LI Xiaobin,YU Ming,et al.Treatment of Lung Cancer Based on Theory of "Generation of Five Elements" of Lung, Spleen, and Kidney[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(15):172-178. DOI: 10.13422/j.cnki.syfjx.20230630.
原发性肺癌作为全球范围内最常诊断的恶性肿瘤和癌症致死的首要因素之一,已经严重危害到了人类的生命安全。在我国,受地域差异影响,肺癌对于各地区的影响虽有所不同,但仍是病死率最高的恶性肿瘤。西医治疗肺癌往往存在一定的局限性,现阶段西医、中医配合治疗,或者直接采用中医治疗已经成为肺癌治疗的必然趋势。中医治病以整体观念为指导思想,整体观念包括五脏一体观和形神一体观,故中医对于肺癌的治疗讲求虽病一脏,应治全身,与五脏一体观理论相对应。即对于肺癌的治疗除了治疗肺脏之外,还应同治脾、肾。肺、脾、肾三脏在五行上分别对应金、土、水,依据五行相生关系,土生金,土为金之母,金生水,水为金之子,益火(肾)补土,通过补益肺的母及子,治疗肺脏疾病,相生相化,生化不绝。肺癌耗气日久必累及母脏,子盗母气,应虚则补其母,故采用培土生金法以扶正治本,土旺金自生,自去肺虚之候。肺肾亏虚是肺癌发病的重要因素,阴虚日久则金不生水,水不润金,故应母子同补,采用金水相生法以滋肾润肺,肺阴得润,肺自宣降有力。脾为肺之母,肾为肺之子,肺癌日久则致母亏子虚,故采用益火补土法以益肾健脾,先后天皆充,肺亦调节有度。肺脾肾三脏调和则气血化生有源,气血阴阳平衡,机体自我康复能力再现,治疗肺癌会取得更好的疗效。根据中医整体观念,安周身以治肺癌,治疗肺癌时肺脾肾三脏同治,以肺脾肾为中轴,采用培土生金、益火补土、金水相生的治法治疗肺癌可以取得良好的治疗效果。
Primary lung cancer, as one of the most commonly diagnosed malignancies and the top leading cause of cancer death worldwide, has seriously endangered human life. In China, due to regional differences, although the impact of lung cancer on different regions is different, it still has the highest mortality among malignant tumors. Western medicine often has certain limitations in the treatment of lung cancer. At present, the combination of western medicine and traditional Chinese medicine (TCM) or the direct application of TCM has become an inevitable trend in the treatment of lung cancer. TCM treatment is guided by the holistic view, which includes the view of integration of the five internal organs and the integration of the body and spirit. Therefore, the treatment of lung cancer in TCM emphasizes that although the disease is located in one organ, the whole body should be treated, which corresponds to the theory of the view of integration of the five internal organs. In addition to the lung in the treatment of lung cancer, the spleen and kidney should also be treated. The lung, spleen, and kidney correspond to metal, earth, and water, respectively on the five elements. According to the generation relationship of the five elements, since earth generates metal and metal generates water, earth is the mother of metal and water is the child of metal. Therefore, benefiting fire (kidney) can replenish earth. Tonifying the mother and son of the lung can treat lung diseases, reflecting mutual generation and transformation and ceaseless generation and transformation. Long-term consumption of Qi by lung cancer can affect mother-organ. In the context of disorder of child-organ affecting mother-organ, mother-organ should be tonified in the face of deficiency. The treatment principle of banking up earth to generate metal should be followed to reinforce healthy Qi and treat the root. Effulgent earth can promote the generation of metal and the syndrome of lung deficiency can be resolve. The lung and kidney deficiency is an important factor in the incidence of lung cancer. Yin deficiency for a long time can hinder the generation of water by metal, resulting in failure of water in moistening metal, so both mother organ and child organ should be tonified. The treatment principle of mutual generation between metal and water should be employed to moisten the kidney and lung, thereby facilitating the vigorous ventilation and descending of the lung. The spleen is the mother organ of the lung, and the kidney is the child organ of the lung. Long-term lung cancer causes the deficiency of the mother and child organs, so the treatment principle of replenishing fire to nourish earth should be adopted to benefit the kidney and tonify the spleen. Therefore, innate basis and acquired foundation are both filled, and the lung can be regulated properly. When the lung, spleen, and kidney are harmonized, the generation and transformation of Qi and blood are active, and the Yin and Yang of Qi and blood are balanced, so the self-rehabilitation ability of the body is ensured, and the treatment of lung cancer will achieve a good curative effect. According to the holistic view of TCM, the whole body should be regulated to treat lung cancer. The lung, spleen, and kidney are all treated in the treatment of lung cancer. With the lung, spleen, and kidney as the central axis, the treatment principles of banking up earth to generate metal, replenishing fire to nourish earth, and mutual generation between metal and water should be followed in the treatment of lung cancer, and a good therapeutic effect can be achieved.
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