Objective

2

To systematically review the ancient and modern literature about Maimendongtang

so as to provide a scientific basis for the modern clinical application and preparation research and development of Maimendongtang.

Method

2

The Chinese Medical Code (version 5) was searched with "Maimendongtang" as the keyword. The modern clinical studies of Maimendongtang were retrieved from CNKI with “Maimendongtang” as the keyword and the time interval from January 1

1975 to December 31

2022. The articles involving the main symptoms

herb composition

dosage

and decocting and medication methods of Maimendongtang were selected and screened according to the inclusion and exclusion criteria. Finally

the information including the book name

indications

herbs

dosage

and decocting and medication methods were included to summarize the ancient and modern application of Maimendongtang.

Result

2

A total of 357 publications of Maimendongtang were included

involving 115 ancient books. Maimendongtang was first published in the

Synopsis of the Golden Chamber

by ZHANG Zhongjing in the Han dynasty. It is composed of Ophiopogonis Radix

Pinelliae Rhizoma

Ginseng Radix et Rhizoma

Semen Oryzae Sativae

Jujubae Fructus

and Glycyrrhizae Radix et Rhizoma. Despite the slight changes during the inheritance by later generations

the indications

herb composition

dosage

and decocting and medication methods of this formula were generally consistent with those in the

Synopsis of the Golden Chamber

. A total of 182 modern articles were included to analyze the clinical application of Maimendongtang. This formula was mainly used to treat respiratory system diseases

digestive system diseases

tumor-related diseases

etc.

Conclusion

2

According to the textual research on the ancient and modern literature

the composition

dosage

indications

and decocting and medication methods of Maimendongtang are basically consistent with those recorded in the

Synopsis of the Golden Chamber

. The modern clinical application not only follows the main indications but also expands the clinical application scope of this formula

which is mainly used to treat patients with the syndrome of yin deficiency of lung and stomach. The modern clinical application of Maimendongtang has promoted the inheritance and innovation of classic famous prescriptions and provided a scientific basis for the drug research and development.