Syndrome Differentiation and Treatment of Obesity from "Orchids to Eliminate Stagnant Qi"

ZHOU Jingxin; LU Yizhen; YANG Jie; JIN Jian; MIAO Juan; ZHANG Yan

doi:10.13422/j.cnki.syfjx.20231330

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Syndrome Differentiation and Treatment of Obesity from "Orchids to Eliminate Stagnant Qi"

更新时间：2023-07-18

- Syndrome Differentiation and Treatment of Obesity from "Orchids to Eliminate Stagnant Qi"
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 29, Issue 16, Pages: 72-78(2023)
- 作者机构：
  
  1.北京中医药大学东直门医院，北京 101121
  2.首都医科大学附属北京友谊医院，北京 100050
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20231330
  CLC： R2-0;R22;R242;R2-031;R285.5
- Published：20 August 2023，
  
  Published Online：08 June 2023，
  
  Received：17 April 2023，
- 稿件说明：
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周静鑫,鲁轶臻,杨杰等.从“兰除陈气”探析肥胖辨治[J].中国实验方剂学杂志,2023,29(16):72-78.

ZHOU Jingxin,LU Yizhen,YANG Jie,et al.Syndrome Differentiation and Treatment of Obesity from "Orchids to Eliminate Stagnant Qi"[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(16):72-78.
周静鑫,鲁轶臻,杨杰等.从“兰除陈气”探析肥胖辨治[J].中国实验方剂学杂志,2023,29(16):72-78. DOI： 10.13422/j.cnki.syfjx.20231330.

ZHOU Jingxin,LU Yizhen,YANG Jie,et al.Syndrome Differentiation and Treatment of Obesity from "Orchids to Eliminate Stagnant Qi"[J].Chinese Journal of Experimental Traditional Medical Formulae,2023,29(16):72-78. DOI： 10.13422/j.cnki.syfjx.20231330.

摘要

肥胖是由遗传、饮食结构、生活方式与行为、心理、环境及社会等多因素引起能量过剩致体内脂肪异常或过多堆积的一种慢性、易反复、进行性的代谢性疾病。肥胖作为主要危险因素，增加了2型糖尿病、高血压、心血管疾病、卒中、部分恶性肿瘤等多种慢性疾病的发病风险。全球肥胖发病率逐年上升，随着人民生活水平不断提高，我国已有超过半数以上的成年人存在超重及肥胖，严重危害人民健康，增加社会与经济负担，成为亟待解决的重大公共卫生问题。肥胖，最早见于《黄帝内经》，有“肥贵人，则高梁之疾也”之描述，并提出“肥者令人内热，甘者令人中满，故其气上溢，转为消渴。治之以兰，除陈气也”。膏粱酒食之积不化而成陈气，故肥胖为“陈气”之疾。肥胖是因嗜食膏粱酒酪，辛辣浓味，生冷寒凉，甜腻食物，或饱食安逸少动、久坐熬夜，或喜、怒、忧、思、恐等五志过及，或因先天禀赋异常，致脾胃受纳运化失常，小肠化物泌别吸收失调，陈气内生，堆积于脏腑与肌肤，而见形体肥满。食饮入口，离不开胃之受纳腐熟、小肠之受盛泌别清浊、脾之转输，其病位在脾、胃、小肠。兰者，兰泽香草也，狭义即佩兰、泽兰，芳香之品，能畅气机，除陈腐，涤垢腻；广义凡气味香辛，可醒脾升清，和胃降浊，助小肠化物泌别如常，逐退盈余者，皆谓之“兰”。因此，肥胖当治以“兰除陈气”，旨在运用辛香之品调整脾、胃、小肠之功能，逐退食湿痰浊郁热等盈余，以复中焦升降平衡，肥者不肥也。

Abstract

Obesity is a chronic， recurrent， and progressive metabolic disorder characterized by the abnormal or excessive accumulation of body fat caused by multiple factors such as genetics， dietary structure， lifestyle and behavior， psychology， environment， and society， leading to an energy surplus. Obesity is a major risk factor that increases the risk of developing various chronic diseases， including type 2 diabetes， hypertension， cardiovascular diseases， stroke， and certain malignancies. The global incidence of obesity is increasing year by year. With the continuous improvement of people's living standards， more than half of adults in China are now overweight or obese， posing a serious threat to people's health and increasing the social and economic burden. It has become a pressing major public health issue that needs to be addressed urgently. The concept of obesity can be traced back to the

Huangdi’s Internal Classic

（

Huang Di Nei Jing

）， which describes it as "the problems in fat and affluent people are caused by excessive taking of rich food"， and suggests that ''frequent intake of rich and greasy foods can produce interior heat. Sweet flavor causes chest fullness. That is why its spleen-Qi flows upwards and changes into consumption-thirst disease. It can be treated by Eupatorii Herba which is used to remove stagnant Qi''. The stagnant qi is caused by the transformation failure of rich and greasy food and wine， so obesity is the disease of stagnant qi. Obesity is caused by indulging in rich and greasy food， wine， spicy and flavorful foods， raw and cold foods， and sweet and greasy foods， or overeating and leading a sedentary lifestyle， staying up late， or experiencing emotional imbalances such as excessive joy， anger， worry， pensiveness， and fear. It can also be caused by congenital abnormalities， leading to improper functioning of the spleen and stomach， dysregulation of the absorption and secretion of the small intestine， and the accumulation of stagnant Qi in the organs and muscles， resulting in a plump physique. The intake of food and drink depends on the functions of the stomach in receiving and decomposing， the small intestine in absorbing and secreting， and the spleen in transforming and transporting. The affected organs in obesity are the spleen， stomach， and small intestine. Orchids， specifically Eupatorii Herba and Lycopi Herba， are aromatic herbs that can regulate the smooth flow of Qi， eliminate stagnation， and cleanse impurities. In a broader sense， any aromatic and pungent substance that can invigorate the spleen， promote clarity， harmonize the stomach， reduce turbidity， and assist in the normal secretion and absorption functions of the small intestine， thereby eliminating excess， is referred to as orchid. Therefore， the treatment principle for obesity is to use ''orchids to eliminate stagnant Qi''， aiming to regulate the functions of the spleen， stomach， and small intestine using aromatic and pungent substances， gradually eliminating excessive dampness， phlegm， turbidity， and heat， and restore the balance of the middle energizer. This way， individuals who are obese can achieve a non-obese state.

关键词

肥胖“陈气”之疾脾、胃、小肠“兰除陈气”

Keywords

obesitystagnant qispleen， stomach， and small intestineorchids to eliminate stagnant qi

references

PAN X F， WANG L， PAN A. Epidemiology and determinants of obesity in China ［J］. Lancet Diabetes Endocrinol， 2021，9（6）：373-392.

HARIHARAN R，ODJIDJA E N，SCOTT D，et al.The dietary inflammatory index， obesity， type 2 diabetes， and cardiovascular risk factors and diseases［J］.Obes Rev，2022，23（1）：e13349.

LITWIN M，KUŁAGA Z.Obesity， metabolic syndrome， and primary hypertension［J］.Pediatr Nephrol，2021，36（4）：825-837.

POWELL-WILEY T M，POIRIER P，BURKE L E，et al.Obesity and cardiovascular disease： A scientific statement from the american heart association［J］.Circulation，2021，143（21）：e984-e1010.

CHEN Z， IONA A， PARISH S， et al. Adiposity and risk of ischaemic and haemorrhagic stroke in 0.5 million Chinese men and women： A prospective cohort study［J］. Lancet Glob Health， 2018，6（6）：e630-e640.

De PERGOLA G， SILVESTRIS F. Obesity as a major risk factor for cancer［J］. J Obes， 2013， doi： 10.1155/2013/291546http://dx.doi.org/10.1155/2013/291546.

ENGIN A. Obesity-associated breast cancer： Analysis of risk factors［J］. Adv Exp Med Biol， 2017，960：571-606.

BROWN K A. Metabolic pathways in obesity-related breast cancer［J］. Nat Rev Endocrinol， 2021，17（6）：350-363.

胡美玉，朱叶珊，于文霞.“除陈气”理论在糖尿病治疗中的应用［J］.中医临床研究， 2022，14（18）：8-9.

薛泰骑，王世东，陈小愚，等.吕仁和分期辨治糖尿病经验阐介［J］.中医杂志，2022，63（5）：412-415.

马晓明.“消渴治之以兰”浅议［J］.光明中医，2012，27（4）：649-650.

赵柏恒."除陈气"法对2型糖尿病的影响［J］.河南中医学院学报，2009，24（4）：80-81.

吕久省.吕靖中运用《内经》"除陈气"治消渴经验［J］.中医杂志，2004，45（9）：665.

杨惠琴，王晓峰，王卫群.谈糖尿病辨治的"治之以兰，除陈气也"［J］.新疆中医药，2001，19（2）：6-7.

马金鹏，吴深涛，郭立平.基于《内经》糖尿病前期的论述考辨其防治措施［J］.中华中医药学刊，2009，27（6）：1211-1212.

李涛.运用“除陈气”治疗消渴病的体会［J］.中医研究，1998（3）：50-51.

李浩冉，马蕊芳，魏亚莉等.芦少敏主任医师基于《内经》“除陈气”“木郁达之”理论治疗糖尿病前期临床经验［J］.亚太传统医药，2018，14（10）：120-122.

甘洪桥，伍冰，苟文伊.基于《内经》“治之以兰”论治肥胖型糖尿病前期［J］.中国医药科学，2023，13（1）：99-102，170.

佚名.黄帝内经·素问［M］. 北京：人民卫生出版社， 2005：1，12，20，59，93.

尤乘.寿世青编［M］. 北京：中华书局， 2013：45.

李鹏飞.三元参赞延寿书［M］. 北京：中国医药科技出版社， 2021：48.

叶天士.临证指南医案［M］. 北京：人民卫生出版社， 2006：273.

王友发，孙明晓，杨月欣，等.中国肥胖预防和控制蓝皮书［M］. 北京：北京大学医学出版社， 2019.

李东垣.脾胃论［M］. 北京：人民卫生出版社， 2005：7-8，61，64，80，75.

丹波元简.素问识［M］. 北京：中国医药科技出版社， 2019：45.

李梴.医学入门［M］. 北京：人民卫生出版社， 2006：139.

王子接.绛雪园古方选注［M］. 北京：中国中医药出版社， 2019：127.

何梦瑶.医碥［M］. 北京：中国中医出版社， 2009：169.

吴瑭.温病条辨［M］. 北京：人民卫生出版社， 2005：191，174.

吴崑.医方考［M］. 北京：中国医药科技出版社， 2022：81.

汪昂.本草备要［M］. 北京：人民卫生出版社， 2005：61-62.

李时珍.本草纲目［M］. 北京：人民卫生出版社， 1982：901-903.

张洁，严小军，卢晓南，等.佩兰对营养性肥胖大鼠的干预作用及代谢组学研究［J］.中药药理与临床，2018，34（4）：96-100.

任强，王红玲，周学刚，等.泽兰的化学成分、质量分析及药理作用研究进展［J］.中国药房，2015，26（18）：2588-2592.

吴谦.医宗金鉴［M］. 北京：中国中医药出版社， 2006：647，647，612.

LI Y， LI Z， CHEN B， et al. Ultrasonic assisted extraction， characterization and gut microbiota-dependent anti-obesity effect of polysaccharide from Pericarpium Citri Reticulatae 'Chachiensis'［J］. Ultrason Sonochem， 2023， doi： 10.1016/j.ultsonch.2023.106383http://dx.doi.org/10.1016/j.ultsonch.2023.106383.

KIM Y J，SHIN Y O，HA Y W，et al.Anti-obesity effect of Pinellia ternata extract in Zucker rats［J］.Biol Pharm Bull，2006，29（6）：1278-1281.

朱丹溪.丹溪心法［M］. 北京：人民卫生出版社， 2005：33.

JIAO P，TSENG-CRANK J，CORNELIUSEN B，et al.Lipase inhibition and antiobesity effect of Atractylodes lancea［J］.Planta Med，2014，80（7）：577-582.

PARK Y J， SEO M G， COMINGUEZ D C， et al. Atractylodes chinensis water extract ameliorates obesity via promotion of the SIRT1/AMPK expression in high-fat diet-induced obese mice［J］. Nutrients， 2021，13（9）：2992.

李天庆.防己黄芪汤对于内脏脂肪肥胖型糖尿病患者的疗效［J］.国外医学：中医中药分册，1997（5）：39.

刘晓倩，金昕，侯瑞芳，等.从肥胖表型体系再评价防己黄芪汤的减重效应［J］.世界中西医结合杂志，2016，11（11）：1610-1614.

NISSANKARA RAO L S，KILARI E K，KOLA P K.Protective effect of Curcuma amada acetone extract against high-fat and high-sugar diet-induced obesity and memory impairment［J］.Nutr Neurosci，2021，24（3）：212-225.

王以撒，李文兰，孙加琳，等.天然产物抗肥胖活性的研究进展［J］.中药药理与临床，2021，37（3）：235-240.

王会宁，李淑颖，吴亚妮，等.复方芳香植物提取物对营养型肥胖大鼠的减肥作用［J］.中国实验方剂学杂志，2012，18（1）：168-172.

汤涛，董伟，陈绪龙，等.芳香中药精油干预代谢综合征的研究进展［J］.中草药，2021，52（19）：6088-6095.

谭珍媛，邓家刚，张彤，等.中药厚朴现代药理研究进展［J］.中国实验方剂学杂志，2020，26（22）：228-234.

陈士铎.本草新编［M］. 北京：中国中医药出版社， 2008：71.

刘莉，李卫忠，王师菡，等.中医药多靶点干预代谢综合征机制研究概述［J］.中国实验方剂学杂志，2021，27（3）：214-221.

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