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Traditional Chinese Medicine Treats Ischemic Stroke by Regulating mTOR Signaling Pathway: A Review
更新时间:2024-04-30
    • Traditional Chinese Medicine Treats Ischemic Stroke by Regulating mTOR Signaling Pathway: A Review

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    • 科技新闻播报:缺血性脑卒中(IS)作为严重的脑血管疾病,其治疗一直是医学界的关注焦点。目前,尽管静脉溶栓是主要的治疗手段,但其存在的出血风险、治疗窗口狭窄等问题限制了其应用。因此,寻求更有效的脑保护策略对IS的预后至关重要。在这方面,研究发现哺乳动物雷帕霉素靶蛋白(mTOR)信号通路是改善IS脑损伤的重要通道机制之一。中医在IS的治疗中展现了丰富的干预手段和独特优势,尤其在患者症状改善和生活质量提升方面。诸多研究表明,中药通过调控激活mTOR信号通路,能够干预和调节细胞自噬、抑制神经细胞凋亡、抑制氧化应激和炎症反应,从而有效减轻IS导致的脑损伤。这为中医药治疗IS提供了新的治疗策略和思路,也展现了中医药在神经系统疾病领域的潜力。综上所述,mTOR信号通路在IS发病中扮演重要角色,而中药通过调控该通路为IS的治疗开辟了新的方向。未来,中医药治疗IS的潜力将进一步得到挖掘和应用,为患者带来更大的治疗益处。
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 11, Pages: 265-272(2024)
    • DOI:10.13422/j.cnki.syfjx.20232029    

      CLC: R2-0;R22;R242;R287;R651.1
    • Published:05 June 2024

      Published Online:23 August 2023

      Received:29 June 2023

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  • MA Yugang,WANG Xingchen,WANG Xuebin,et al.Traditional Chinese Medicine Treats Ischemic Stroke by Regulating mTOR Signaling Pathway: A Review[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(11):265-272. DOI: 10.13422/j.cnki.syfjx.20232029.

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Related Author

MA Yugang
WANG Xingchen
WANG Xuebin
LI Yahui
YU Yunfeng
HU Gang
ZHOU Manli
ZHOU Xiahui

Related Institution

Shandong University of Traditional Chinese Medicine
The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine
School of Traditional Chinese Medicine,Hunan University of Chinese Medicine
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