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Modified Weijingtang Regulates Pyroptosis of Macrophages via Caspase-1/GSDMD Pathway
更新时间：2024-04-30
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    • Modified Weijingtang Regulates Pyroptosis of Macrophages via Caspase-1/GSDMD Pathway

    • “加味苇茎汤对RAW264.7巨噬细胞焦亡模型的干预作用及其对焦亡通路的影响被深入研究。科研人员通过模拟巨噬细胞焦亡模型，发现加味苇茎汤能有效减轻细胞焦亡状态，改善细胞形态。此外，研究还揭示了加味苇茎汤可能通过下调Caspase-1/GSDMD通路，抑制巨噬细胞焦亡，减少炎症因子IL-18和IL-1β的释放。这一发现为非酒精性脂肪性肝炎的治疗提供了新的思路和方法，有望为相关领域的研究和发展奠定基础。”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 11, Pages: 27-33(2024)

    • DOI：10.13422/j.cnki.syfjx.20232422    

      CLC： R2-0;R22;R242;R285.5

    • Published：05 June 2024，

      Published Online：01 November 2023，

      Received：16 July 2023，

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  • SHANG Dongfang,ZHAO Chenlu,WANG Siying,et al.Modified Weijingtang Regulates Pyroptosis of Macrophages via Caspase-1/GSDMD Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(11):27-33. DOI： 10.13422/j.cnki.syfjx.20232422.

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