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Effect and Mechanism of Water Extract of Mori Folium on Oxidative Stress in Adipose Tissue of T2DM Mice
更新时间：2024-04-30
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    • Effect and Mechanism of Water Extract of Mori Folium on Oxidative Stress in Adipose Tissue of T2DM Mice

    • “一项关于桑叶水提物对2型糖尿病小鼠脂肪组织氧化应激影响的研究取得了重要进展。研究团队通过精心设计的实验，发现桑叶水提物能够显著降低糖尿病小鼠的空腹血糖和口服糖耐量水平，同时减少脂肪组织指数。这一作用机制与桑叶水提物提升血清抗氧化物酶SOD、GSH含量，降低氧化应激损伤标志物MDA水平有关。更重要的是，研究还揭示了桑叶水提物能够上调脂肪组织中SIRT1蛋白的表达，并下调NOX4蛋白的表达，这为进一步理解桑叶水提物改善糖尿病的作用提供了重要线索。这一发现不仅为糖尿病治疗提供了新的潜在药物，也为桑叶资源的开发利用提供了科学依据。”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 11, Pages: 43-50(2024)

    • DOI：10.13422/j.cnki.syfjx.20240428    

      CLC： R2-0;R22;R242;R285.5;R856.2

    • Published：05 June 2024，

      Published Online：08 January 2024，

      Received：18 October 2023，

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  • ZHANG Huilin,AN Yongcheng,HE Changhao,et al.Effect and Mechanism of Water Extract of Mori Folium on Oxidative Stress in Adipose Tissue of T2DM Mice[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(11):43-50. DOI： 10.13422/j.cnki.syfjx.20240428.

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