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Mechanism of Polyphyllin Ⅱ in Induction of Ferroptosis in Hepatocellular Carcinoma HepG2 Cells
更新时间：2024-07-31

    • Mechanism of Polyphyllin Ⅱ in Induction of Ferroptosis in Hepatocellular Carcinoma HepG2 Cells

    • “Zhonglou Saponin II (PP II) induces ferroptosis in HepG2 liver cancer cells by regulating the p53/SLC7A11/GPX4 signaling pathway axis, promoting ACSL4 expression and cell uptake of Fe3+, and disrupting the antioxidant system.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 17, Pages: 105-112(2024)

    • DOI：10.13422/j.cnki.syfjx.20240629    

      CLC： R2-0;R22;R242;R285.5;R735.7

    • Received：16 November 2023，

      Published Online：19 February 2024，

      Published：05 September 2024

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  • ZHANG Huizhong,NI Jian,PENG Hulinyue,et al.Mechanism of Polyphyllin Ⅱ in Induction of Ferroptosis in Hepatocellular Carcinoma HepG2 Cells[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(17):105-112. DOI： 10.13422/j.cnki.syfjx.20240629.

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