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Extraction Process and Mechanism of Active Ingredients of Mori Folium for Lowering Blood Glucose： A Review
更新时间：2024-04-30
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    • Extraction Process and Mechanism of Active Ingredients of Mori Folium for Lowering Blood Glucose： A Review

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    • “科技新闻播报：桑叶，这一古老的中药材，如今在糖尿病研究领域展现出新的活力。桑叶具有疏散风热、清肺润燥、平肝明目、凉血止血等多种功效，尤其是其调节血糖的作用备受关注。通过检索中国知网、Web of Science及PubMed等数据库，相关研究发现，桑叶中的黄酮、生物碱、多糖、酚类等成分在降糖方面表现出显著效果。桑叶降糖机制涉及多成分、多通路、多靶点，主要通过改善糖脂代谢、保护胰腺β细胞、减轻胰岛素抵抗等方式减轻高血糖对机体的损害。为了更好地提取桑叶中的降糖活性成分，研究者们不断探索新的提取工艺，包括传统的溶剂提取法、超声辅助、微波辅助等，以及新兴的CO2超临界流体萃取法、酶解法、浊点萃取法等。通过对桑叶降糖有效部位的研究，分析各类降糖成分适用的提取方法，对比传统与新兴提取工艺的优缺点，有望为桑叶降糖有效部位提取工艺的优化、降糖化学成分及其作用机制研究、新药开发和临床应用提供有效的理论支撑。这一研究成果不仅为糖尿病治疗提供了新的思路，也为中药材的现代化应用开辟了新的方向。”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 11, Pages: 60-69(2024)

    • DOI：10.13422/j.cnki.syfjx.20240825    

      CLC： R2-0;R22;R242;R285.5;R587.1

    • Published：05 June 2024，

      Published Online：27 February 2024，

      Received：10 December 2023，

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  • XIE Jiamei,ZHANG Huilin,HUANG Yan,et al.Extraction Process and Mechanism of Active Ingredients of Mori Folium for Lowering Blood Glucose： A Review[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(11):60-69. DOI： 10.13422/j.cnki.syfjx.20240825.

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