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Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain
更新时间：2024-11-18

    • Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain

    • “Ruyi Zhenbao Pill can effectively alleviate pain hypersensitivity and spinal sensitization in post-stroke central pain mice. Its mechanism involves regulating CXCL16-CXCR6 ligand receptor, inhibiting infiltration and activation of microglia and macrophages, and activating dendritic cells, endothelial cells, and T cells.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 24, Pages: 36-46(2024)

    • DOI：10.13422/j.cnki.syfjx.20241743    

      CLC： R2-0;R33;R742;R24

    • Received：08 September 2024，

      Published Online：28 October 2024，

      Published：20 December 2024

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  • HUANG Aoqing,WANG Wenli,LIU Ying,et al.Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(24):36-46. DOI： 10.13422/j.cnki.syfjx.20241743.

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Related Author

WANG Wenli
ZHANG Guoxin
LIN Na
LIN Ya
LI Sainan
ZHANG Guixian
SHEN Hongsheng
WANG Manxue

Related Institution

College of Pharmacy， Fujian University of Traditional Chinese Medicine
Graduate School， Tianjin Medical University
Tianjin Institute of Medical and Pharmaceutical Sciences
State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture，Nanjing University of Chinese Medicine，Jiangsu Kanion Pharmaceutical Co. Ltd.
Kanion School of Chinese Materia Medica，Nanjing University of Chinese Medicine
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