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Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain
更新时间：2024-11-18

    • Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain

    • “Ruyi Zhenbao Pill can effectively alleviate pain hypersensitivity and spinal sensitization in post-stroke central pain mice. Its mechanism involves regulating CXCL16-CXCR6 ligand receptor, inhibiting infiltration and activation of microglia and macrophages, and activating dendritic cells, endothelial cells, and T cells.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 24, Pages: 36-46(2024)

    • DOI：10.13422/j.cnki.syfjx.20241743    

      CLC： R2-0;R33;R742;R24

    • Received：08 September 2024，

      Published Online：28 October 2024，

      Published：20 December 2024

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  • HUANG Aoqing,WANG Wenli,LIU Ying,et al.Pharmacodynamic Characteristics and Neuroinflammatory Mechanisms of Ruyi Zhenbaowan in Treating Nociceptive Hypersensitivity and Central Sensitisation of Spinal Cord in Mouse Model of Central Post-stroke Pain[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(24):36-46. DOI： 10.13422/j.cnki.syfjx.20241743.

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Related Author

WANG Wenli
ZHANG Guoxin
LIN Na
LIN Ya
LI Sainan
ZHANG Guixian
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Related Institution

College of Pharmacy， Fujian University of Traditional Chinese Medicine
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The First Clinical Medical College of Shaanxi University of Chinese Medicine
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