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Differences and Mechanisms of Combined Use of "Raw and Fried Ziziphi Spinosae Semen" in Anmeidan and Its Disassembled Prescriptions in Improving Anxiety and Cognitive Impairment in Insomnia Rat Model Based on Serum Metabolomics
更新时间：2025-04-18

    • Differences and Mechanisms of Combined Use of "Raw and Fried Ziziphi Spinosae Semen" in Anmeidan and Its Disassembled Prescriptions in Improving Anxiety and Cognitive Impairment in Insomnia Rat Model Based on Serum Metabolomics

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    • “The latest research has found that the combination of "raw and cooked sour jujube kernels" in Anmei Dan has a better effect on improving anxiety and cognitive impairment in insomnia rats than the split formula group, which may be related to metabolic pathways such as phenylalanine, tryptophan, and 5-hydroxytryptamine.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 10, Pages: 36-43(2025)

    • DOI：10.13422/j.cnki.syfjx.20242336    

      CLC： R259;R285;R242

    • Received：21 October 2024，

      Accepted：20 December 2024，

      Published Online：25 December 2024，

      Published：20 May 2025

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  • SUN Kang,XU Bo,YE Zijing,et al.Differences and Mechanisms of Combined Use of "Raw and Fried Ziziphi Spinosae Semen" in Anmeidan and Its Disassembled Prescriptions in Improving Anxiety and Cognitive Impairment in Insomnia Rat Model Based on Serum Metabolomics[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(10):36-43. DOI： 10.13422/j.cnki.syfjx.20242336.

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Related Author

LI Feizhou
XU Bo
YE Zijing
LI Lianyu
ZHANG Andong
WANG Ping
CHEN Linlin
ZHAO Jie

Related Institution

Hubei Provincial Hospital of Traditiona1 Chinese Medicine
Hubei University of Chinese Medicine
Shiyan Taihe Hospital
Experimental Research Center，China Academy of Chinese Medical Sciences
Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences
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