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Mechanism of Qingrun Prescription-containing Serum Improving Insulin Resistance in HepG2 Cells via Branched-chain α-keto Acid Dehydrogenase Regulation of Branched-chain Amino Acids （BCAAs）/mTOR Pathway
更新时间：2025-04-02
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    • Mechanism of Qingrun Prescription-containing Serum Improving Insulin Resistance in HepG2 Cells via Branched-chain α-keto Acid Dehydrogenase Regulation of Branched-chain Amino Acids （BCAAs）/mTOR Pathway

    • “The latest research has found that the serum containing Qingrun Formula can improve insulin resistance in HepG2 cells, possibly by upregulating BCKDH to inhibit BCAAs and BCKAs, thereby inhibiting mTOR pathway activation and improving insulin resistance mediated by BCAAs metabolic reprogramming.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 9, Pages: 90-98(2025)

    • DOI：10.13422/j.cnki.syfjx.20250201    

      CLC： R243;R285;R289

    • Received：26 November 2024，

      Accepted：2025-01-07，

      Published Online：08 January 2025，

      Published：05 May 2025

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  • BU Xiangwei,HAO Xiaohui,ZHANG Runyun,et al.Mechanism of Qingrun Prescription-containing Serum Improving Insulin Resistance in HepG2 Cells via Branched-chain α-keto Acid Dehydrogenase Regulation of Branched-chain Amino Acids （BCAAs）/mTOR Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(09):90-98. DOI： 10.13422/j.cnki.syfjx.20250201.

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