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Mechanism of Huanglian Jiedutang in Improving Pyroptosis, Neuroinflammation, and Learning and Cognitive Functions in APP/PS1 Mice Based on NLRP3/Caspase-1/GSDMD Pathway
更新时间:2025-05-16
    • Mechanism of Huanglian Jiedutang in Improving Pyroptosis, Neuroinflammation, and Learning and Cognitive Functions in APP/PS1 Mice Based on NLRP3/Caspase-1/GSDMD Pathway

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    • The latest research has found that Huanglian Jiedu Tang improves the learning and memory ability of Alzheimer's disease mice by inhibiting the NLRP3/Caspase-1/GSDMD pathway, and inhibits neuronal loss and synaptic damage.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 12, Pages: 11-19(2025)
    • DOI:10.13422/j.cnki.syfjx.20250301    

      CLC: R285;R259;R289
    • Received:18 November 2024

      Accepted:13 February 2025

      Published Online:14 February 2025

      Published:20 June 2025

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  • CHENG Wei,YANG Shuo,HE Zhangxin,et al.Mechanism of Huanglian Jiedutang in Improving Pyroptosis, Neuroinflammation, and Learning and Cognitive Functions in APP/PS1 Mice Based on NLRP3/Caspase-1/GSDMD Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(12):11-19. DOI: 10.13422/j.cnki.syfjx.20250301.

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