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Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis
更新时间：2026-02-28

    • Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis

    • “Experts have studied the mechanism of using modified Duhuo parasitic mixture to treat synovial lesions in knee osteoarthritis. Animal experiments have shown that it can improve inflammatory response, regulate signaling pathways, inhibit cell apoptosis, and provide new ideas for the treatment of knee osteoarthritis.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 32, Issue 1, Pages: 170-179(2026)

    • DOI：10.13422/j.cnki.syfjx.20250739    

      CLC： R274;R285;R574.62

    • Received：18 February 2025，

      Revised：2025-04-02，

      Accepted：02 April 2025，

      Online First：27 March 2025，

      Published：05 January 2026

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  • YE Zifeng,YUAN Yiwei,QIU Liguo,et al.Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(01):170-179. DOI： 10.13422/j.cnki.syfjx.20250739.

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Related Author

GUO Pengbo
XIAO Changhao
XIA Fei
QIU Chong
WANG Jigang
ZHANG Jin
YANG Lili
ZHENG Canwen

Related Institution

Gannan Medical University
Artemisinin Research Center， Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences
National Clinical Research Center of Traditional Chinese Medicine for Cardiovascular Diseases， Beijing Key Laboratory of Chinese Materia Medica Pharmacology， Xiyuan Hospital of China Academy of Chinese Medical Sciences
The First Clinical Medical College， Shandong University of Traditional Chinese Medicine（TCM）
Affiliated Hospital of Shandong Second Medical University
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