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Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis
更新时间：2025-12-04

    • Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis

    • “The latest research has found that the modified Duhuo parasitic mixture can effectively improve synovial inflammation in knee osteoarthritis. Its mechanism may be through regulating the PI3K/Akt/mTOR signaling pathway, inhibiting cell apoptosis, reducing the release of inflammatory factors, and protecting bone structure.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 32, Issue 1, Pages: 170-179(2026)

    • DOI：10.13422/j.cnki.syfjx.20250739    

      CLC： R274;R285;R574.62

    • Received：18 February 2025，

      Revised：2025-04-02，

      Accepted：02 April 2025，

      Published Online：27 March 2025，

      Published：05 January 2026

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  • YE Zifeng,YUAN Yiwei,QIU Liguo,et al.Effect of Modified Duhuo Jisheng Mixture Regulating PI3K/Akt/mTOR Signaling Pathway on Synoviocyte Pyroptosis in Rabbit Models of Knee Osteoarthritis[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(01):170-179. DOI： 10.13422/j.cnki.syfjx.20250739.

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Related Author

PAN Jing
ZHANG Bing
DANG Chunxiao
LI Jinxiao
LIU Pengfei
YU Xiao
WANG Yuchao
LIU Jinxing

Related Institution

The First Clinical Medical College， Shandong University of Traditional Chinese Medicine（TCM）
Affiliated Hospital of Shandong Second Medical University
Affiliated Hospital of Shandong University of TCM
Institute of Basic Research in Clinical Medicine， China Academy of Chinese Medical Sciences
Beijing Electric Power Hospital of State Grid Corporation of China
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