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Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway
更新时间：2026-01-23

    • Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway

    • “The latest research has found that the combination of Shenmai injection and cisplatin has a synergistic anti-tumor effect on non-small cell lung cancer, which may be related to activating the endoplasmic reticulum stress PERK/eIF2 α/ATF4/CHOP signaling pathway and inducing tumor cell apoptosis.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 32, Issue 4, Pages: 70-78(2026)

    • DOI：10.13422/j.cnki.syfjx.20250825    

      CLC： R256;R285;R563

    • Received：03 December 2024，

      Revised：2025-02-17，

      Accepted：21 February 2025，

      Published Online：24 February 2025，

      Published：20 February 2026

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  • GUO Shengnan,CAO Hao,WANG Dan,et al.Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(04):70-78. DOI： 10.13422/j.cnki.syfjx.20250825.

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