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Modified Buwangsan Ameliorates Cognitive Dysfunction in Rat Model of Type 2 Diabetes Mellitus by Regulating Autophagy in Hippocampus via PI3K/Akt/mTOR Pathway
更新时间:2025-05-30
    • Modified Buwangsan Ameliorates Cognitive Dysfunction in Rat Model of Type 2 Diabetes Mellitus by Regulating Autophagy in Hippocampus via PI3K/Akt/mTOR Pathway

    • Bujisan Jiawei Recipe significantly improves the cognitive function of type 2 diabetes rats, regulates metabolic disorder, reduces blood sugar, reduces oxidative stress, inhibits inflammatory reaction, activates autophagy pathway, promotes neuronal protection and repair, regulates PI3K/Akt/mTOR signal pathway, relieves autophagy inhibition, and alleviates brain tissue damage.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 13, Pages: 104-113(2025)
    • DOI:10.13422/j.cnki.syfjx.20251321    

      CLC: R256;R285;R735.7
    • Received:04 March 2025

      Accepted:23 April 2025

      Published Online:25 April 2025

      Published:05 July 2025

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  • YANG Jie,LIU Tonghua,LIU Wei,et al.Modified Buwangsan Ameliorates Cognitive Dysfunction in Rat Model of Type 2 Diabetes Mellitus by Regulating Autophagy in Hippocampus via PI3K/Akt/mTOR Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(13):104-113. DOI: 10.13422/j.cnki.syfjx.20251321.

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