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Xianlian Jiedu Prescription Suppresses Colorectal Cancer EMT by Blocking Tumor-associated Macrophage-derived CCL5 Secretion and Inhibiting STAT3/β-catenin Signaling Pathway
更新时间:2025-09-08
    • Xianlian Jiedu Prescription Suppresses Colorectal Cancer EMT by Blocking Tumor-associated Macrophage-derived CCL5 Secretion and Inhibiting STAT3/β-catenin Signaling Pathway

    • The latest research has found that Xianlian Jiedu Formula can effectively inhibit the metastasis of colorectal cancer, and its mechanism may involve targeting CCL5 derived from tumor associated macrophages and inhibiting the imbalance of EMT marker expression mediated by STAT3 phosphorylation.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 19, Pages: 138-147(2025)
    • DOI:10.13422/j.cnki.syfjx.20251324    

      CLC: R256;R285;R735.3+5
    • Received:14 March 2025

      Revised:2025-05-16

      Accepted:29 May 2025

      Published Online:03 June 2025

      Published:05 October 2025

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  • QIAN Jingyang,TAO Lihuiping,ZHANG Qinchang,et al.Xianlian Jiedu Prescription Suppresses Colorectal Cancer EMT by Blocking Tumor-associated Macrophage-derived CCL5 Secretion and Inhibiting STAT3/β-catenin Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(19):138-147. DOI: 10.13422/j.cnki.syfjx.20251324.

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