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Mechanisms of Tianma Goutengyin in Alleviating Neuronal Injury in Vascular Dementia Model Rats by Inhibiting A1 Astrocyte Activation via Regulating TNF-α/STAT3/α1ACT Signaling Pathway
更新时间：2026-03-03

    • Mechanisms of Tianma Goutengyin in Alleviating Neuronal Injury in Vascular Dementia Model Rats by Inhibiting A1 Astrocyte Activation via Regulating TNF-α/STAT3/α1ACT Signaling Pathway

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    • “The latest research shows that Tianma Gouteng Drink has significant therapeutic effects on vascular dementia model rats. Research has found that Tianma Gouteng Yin can significantly improve the learning and memory abilities of rats by regulating the TNF - α/STAT3/α 1ACT signaling pathway, inhibiting the activation of A1 type astrocytes, reducing neuronal apoptosis. This achievement provides new ideas and methods for the treatment of vascular dementia.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 32, Issue 7, Pages: 56-65(2026)

    • DOI：10.13422/j.cnki.syfjx.20251539    

      CLC： R242;R285;R289

    • Received：26 May 2025，

      Revised：2025-07-29，

      Accepted：01 August 2025，

      Online First：06 August 2025，

      Published：05 April 2026

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  • WANG Xiaoyan,ZHAO Min,TIAN Feng,et al.Mechanisms of Tianma Goutengyin in Alleviating Neuronal Injury in Vascular Dementia Model Rats by Inhibiting A1 Astrocyte Activation via Regulating TNF-α/STAT3/α1ACT Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(07):56-65. DOI： 10.13422/j.cnki.syfjx.20251539.

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Related Author

WANG Xiaoyan
ZHAO Min
XIAO Min
QU Nan
LIU Fugui
LIU Chixiao
YUAN Bingmao
CHEN Wei

Related Institution

Experimental Animal Center，Hubei University of Chinese Medicine
Department of Encephalopathy，The First Affiliated Hospital of Henan University of Chinese Medicine
The First Affiliated Hospital of Guangxi University of Chinese Medicine
Guangxi University of Chinese Medicine
Shandong University of Traditional Chinese Medicine
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