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Sishenwan Restores Intestinal Barrier in Rat Model of Diarrhea-predominant Irritable Bowel Syndrome Due to Spleen-kidney Yang Deficiency by Regulating Intestinal Flora and Short-chain Fatty Acids
更新时间：2025-10-09

    • Sishenwan Restores Intestinal Barrier in Rat Model of Diarrhea-predominant Irritable Bowel Syndrome Due to Spleen-kidney Yang Deficiency by Regulating Intestinal Flora and Short-chain Fatty Acids

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    • “The latest research has found that Sishen Pill can improve the intestinal barrier function, alleviate diarrhea symptoms and colonic mucosal inflammation in rats with diarrhea predominant irritable bowel syndrome. Its mechanism may be related to regulating the structure of intestinal microbiota and the balance of metabolites.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 21, Pages: 80-89(2025)

    • DOI：10.13422/j.cnki.syfjx.20251698    

      CLC： R242;R256.3;R574

    • Received：13 December 2024，

      Revised：2025-02-17，

      Accepted：21 April 2025，

      Published Online：22 April 2025，

      Published：05 November 2025

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  • ZHANG Qian,LI Siqi,HUYunlian ,et al.Sishenwan Restores Intestinal Barrier in Rat Model of Diarrhea-predominant Irritable Bowel Syndrome Due to Spleen-kidney Yang Deficiency by Regulating Intestinal Flora and Short-chain Fatty Acids[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(21):80-89. DOI： 10.13422/j.cnki.syfjx.20251698.

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Related Author

ZHANG Qian
LI Siqi
HuYunlian
WEN Na
HUANG Chaoqun
LIU Binbin
SU Chengxia
CHEN Yiqin

Related Institution

The First Clinical Medical College，Hubei University of Chinese Medicine，Wuhan 43006l
Hubei Provincial Hospital of Traditional Chinese Medicine/Affiliated Hospital of Hubei University of Chinese Medicine，Wuhan 43006l
Hubei Shizhen Laboratory，Wuhan 43006l
College of Traditional Chinese Medicine，Hubei University of Chinese Medicine，Wuhan 43006l
Gansu University of Chinese Medicine
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