Xiaozheng Zhitong Paste Relieves Bone Cancer Pain in Mice by Alleviating Activation of Microglia in Spinal Cord and Damage to Neurons via Blocking PAR2/NF-κB/NLRP3 Pathway
|更新时间:2026-02-28
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Xiaozheng Zhitong Paste Relieves Bone Cancer Pain in Mice by Alleviating Activation of Microglia in Spinal Cord and Damage to Neurons via Blocking PAR2/NF-κB/NLRP3 Pathway
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“The latest research has found that XZP, a topical formula for relieving symptoms and pain, has significant therapeutic effects on bone cancer pain (BCP). The study established a BCP mouse model and found that XZP can alleviate BCP in mice. Its therapeutic effect may be achieved by blocking the expression of the activated PAR2/NF - κ B/NLRP3 signaling pathway.”
Chinese Journal of Experimental Traditional Medical FormulaeVol. 32, Issue 5, Pages: 91-100(2026)
ZHENG Guangda,MENG Linghan,SHANG Lu,et al.Xiaozheng Zhitong Paste Relieves Bone Cancer Pain in Mice by Alleviating Activation of Microglia in Spinal Cord and Damage to Neurons via Blocking PAR2/NF-κB/NLRP3 Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(05):91-100.
ZHENG Guangda,MENG Linghan,SHANG Lu,et al.Xiaozheng Zhitong Paste Relieves Bone Cancer Pain in Mice by Alleviating Activation of Microglia in Spinal Cord and Damage to Neurons via Blocking PAR2/NF-κB/NLRP3 Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(05):91-100. DOI: 10.13422/j.cnki.syfjx.20251934.
Xiaozheng Zhitong Paste Relieves Bone Cancer Pain in Mice by Alleviating Activation of Microglia in Spinal Cord and Damage to Neurons via Blocking PAR2/NF-κB/NLRP3 Pathway增强出版
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