Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway
|更新时间:2026-03-03
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Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway
“Huazhuo San Jie Qu Bi Fang has significant therapeutic effects on gout bone erosion model rats, which can reduce serum uric acid levels, decrease the secretion of inflammatory factors, and downregulate the expression of bone erosion related proteins. Its mechanism may be related to the inhibition of the PI3K/Akt signaling pathway.”
Chinese Journal of Experimental Traditional Medical FormulaeVol. 32, Issue 7, Pages: 105-117(2026)
ZHENG Zhuoming,LIU Jun,WANG Meiling,et al.Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(07):105-117.
ZHENG Zhuoming,LIU Jun,WANG Meiling,et al.Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(07):105-117. DOI: 10.13422/j.cnki.syfjx.20252325.
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Related Author
ZHENG Zhuoming
LIU Jun
WANG Meiling
CHEN Xiaohua
LI Yuwan
PENG Siwei
ZHANG Yingjie
YANG Ruifang
Related Institution
The First Clinical Medical College,Fujian University of Traditional Chinese Medicine
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Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicine and Rehabilitation,Ministry of Education
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