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Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway
更新时间:2026-03-03
    • Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway

    • Huazhuo San Jie Qu Bi Fang has significant therapeutic effects on gout bone erosion model rats, which can reduce serum uric acid levels, decrease the secretion of inflammatory factors, and downregulate the expression of bone erosion related proteins. Its mechanism may be related to the inhibition of the PI3K/Akt signaling pathway.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 32, Issue 7, Pages: 105-117(2026)
    • DOI:10.13422/j.cnki.syfjx.20252325    

      CLC: R274;R259;R285
    • Received:15 August 2025

      Revised:2025-10-25

      Accepted:31 October 2025

      Online First:13 November 2025

      Published:05 April 2026

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  • ZHENG Zhuoming,LIU Jun,WANG Meiling,et al.Effect and Action Mechanism of Huazhuo Sanjie Chubi Prescription on Gouty Bone Erosion Model Rats Based on PI3K/Akt Signaling Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2026,32(07):105-117. DOI: 10.13422/j.cnki.syfjx.20252325.

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Related Author

ZHENG Zhuoming
LIU Jun
WANG Meiling
CHEN Xiaohua
LI Yuwan
PENG Siwei
ZHANG Yingjie
YANG Ruifang

Related Institution

The First Clinical Medical College,Fujian University of Traditional Chinese Medicine
School of Orthopedics and Traumatology,Fujian University of Traditional Chinese Medicine
Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicine and Rehabilitation,Ministry of Education
College of Rehabilitation Medicine, Fujian University of TCM
School of Orthopedics and Traumatology, Fujian University of Traditional Chinese Medicine(TCM)
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