Analysis on Medication Rules of National Medical Masters in Treatment of Stomachache

Juan-juan LI; Feng-yun WANG; Lin LYU; En-jin ZENG; Lin XU; Xu-dong TANG

doi:10.13422/j.cnki.syfjx.20191455

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Analysis on Medication Rules of National Medical Masters in Treatment of Stomachache

Data Mining | 更新时间：2021-02-09

- Analysis on Medication Rules of National Medical Masters in Treatment of Stomachache
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 21, Pages: 170-175(2019)
- 作者机构：
  
  1.北京中医药大学，北京　 100029；
  2.中国中医科学院　西苑医院，北京100091
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20191455
  CLC： R22; R24; R4; C37; S941.3
- Published：05 November 2019，
  
  Published Online：03 April 2019，
  
  Received：23 January 2019，
- 稿件说明：
扫描看全文
Juan-juan LI, Feng-yun WANG, Lin LYU, et al. Analysis on Medication Rules of National Medical Masters in Treatment of Stomachache. [J]. Chinese Journal of Experimental Traditional Medical Formulae 25(21):170-175(2019)
DOI：

Juan-juan LI, Feng-yun WANG, Lin LYU, et al. Analysis on Medication Rules of National Medical Masters in Treatment of Stomachache. [J]. Chinese Journal of Experimental Traditional Medical Formulae 25(21):170-175(2019) DOI： 10.13422/j.cnki.syfjx.20191455.

摘要

目的：

应用数据挖掘方法分析国医大师治疗胃脘痛的用药规律。

方法：

收集、整理《国医大师验案良方·脾胃卷》《国医大师临床经验实录》等9部著作以及CNKI中收录记载的首批国医大师治疗胃脘痛的医案处方。运用Microsoft Excel 2016进行中药频数、性味归经统计，通过SPSS Clementine 12.0软件所提供的Apriori算法进行关联规则分析，利用SPSS 19.0软件进行因子分析。

结果：

共筛选出175首方剂，含230味中药。使用频数排名前五味的中药分别为甘草、白芍、半夏、白术、茯苓。排名前三位的药性分别为温、平、微寒，药味为甘、苦、辛，归经为脾、胃、肺经。按功效分类，使用频数排名前三位的药物为理气药、补气药、消食药。关联规则分析显示置信度、支持度均最高的为白术→党参-茯苓，体现出国医大师以四君子汤为底方益气的治疗特点；共得到12条强关联药对，最常用的药对为白芍-甘草。因子分析共提取出9个公因子。

结论：

国医大师治疗胃脘痛以调理气机、益气补虚为主，善用芍药甘草汤养血敛阴、柔肝止痛。

Abstract

Objective:

To analyze medication rules of national medical masters in the treatment of stomachache by data mining.

Method:

Prescriptions were collected from 9 works as well as the first batch of national medical masters' medical cases and prescriptions for stomachache recorded in CNKI. Then

Microsoft Excel 2016 was adopted for analyzing the frequencies

properties

flavors and meridian tropisms of herbs

the Apriori algorithm provided by SPSS Clementine 12.0 software was used to analyze association rules of the herbs

and factor analysis was conducted by SPSS 19.0 software.

Result:

A total of 175 prescriptions containing 230 herbs were selected. The top five herbs used in frequency ranking were Glycyrrhizae Radix et Rhizoma

Paeoniae Radix Alba

Pinelliae Rhizoma

Atractylodis Macrocephalae Rhizoma

Poria. The medical properties with high usage frequency were warm

mild and slight cold. The flavors were sweet

bitter and pungent. Meridian tropisms were spleen

stomach and lung. Herbs for regulating Qi

tonifying Qi and promoting digestion ranked top three according to the classification of efficacy. The association rules analysis showed that the highest confidence and support of the related drugs was Atractylodis Macrocephalae Rhizoma→Codonopsis Radix-Poria

which reflected treatment characteristics of national medical masters with Sijunzitang as the basic prescription for tonifying Qi. A total of 12 strongly association rules of 2-drug pairs were obtained by association rules

and the most commonly used of which was Paeoniae Radix Alba-Glycyrrhizae Radix et Rhizoma. Nine common factors were respectively extracted by factor analysis.

Conclusion:

Herbs used in the prescriptions of national medical masters for treatment of stomachache are often with the actions of regulating Qi

invigorating deficiency and benefiting Qi

in addition

Shaoyao Gancaotang is often used to generate Yin and relieve pain.

关键词

胃脘痛慢性胃炎国医大师用药规律中药数据挖掘医案

Keywords

stomachachechronic gastritisnational medical mastersmedication rulestraditional Chinese medicinedata miningmedical cases

references

徐丽丽，薛燕星，张润顺，等．名老中医有效经验方发现研究的探索与实践[J]．中国实验方剂学杂志，2015，21(7)：1-4．

沈娟，杨建宇，徐江雁．国医大师验案良方·脾胃卷[M]．北京：学苑出版社，2010：2-105．

吴少祯．国医大师临床经验实录丛书[M]．北京：中国医药科技出版社，2011．

张文康．中国百年百名中医临床家丛书[M]．北京：中国中医药出版社，2002．

董建华，王永炎，陶广正，等．中国现代名中医医案精粹丛书[M]．北京：人民卫生出版社，2010．

马继松，江厚万，储成志，等．国医大师学术经验研读录(第1～3辑)[M]．北京：人民军医出版社，2010．

徐江雁，刘文礼，杨建宇，等．国家级名老中医·胃病验案良方[M]．郑州：中原农民出版社，2010：1-271．

李艳，朱建平．国医大师学术经验传承录[M]．北京：人民军医出版社，2010．

陆为民，徐丹华，罗斐和，等．国医大师临床丛书[M]．北京：科学出版社，2010．

冯德华，杜惠芳，张东，等．国医大师经验良方赏析丛书[M]．北京：人民军医出版社，2014．

黄兆胜．中药学[M]．北京：人民卫生出版社，2002：1-558．

中华中医药学会脾胃病分会．胃脘痛中医诊疗专家共识意见(2017)[J]．中医杂志，2017，58(13)：1166-1170．

吴智春，于华芸，张成博，等．基于中药整合药理学平台分析黄连汤治疗胃炎的作用机制[J]．中国实验方剂学杂志，2019，25(4)：57-62．

张声生，唐旭东，黄穗平，等．慢性胃炎中医诊疗专家共识意见(2017)[J]．中华中医药杂志，2017，32(7)：3060-3064．

林友宝，孙洁，沈淑华，等．“以通为用”治胃痛—国医大师何任辨治胃痛经验琐谈[J]．中国中医急症，2015，24(8)：1386-1388．

王茂松．徐景藩治疗胃脘痛临床经验[J]．黑龙江中医药，2001(5)：2-3．

季晓杭．左金丸古今文献研究及临床应用探讨[D]．南京：南京中医药大学，2017．

蒋真真，赵智强．从病案窥探周仲瑛教授辨治慢性萎缩性胃炎特色[J]．四川中医，2018，36(1)：164-166．

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