This paper presented the reseach progress of the relationship between vascular endothelial dysfunction and atherosclerosis via literature review and analysis on therapeutic regulation on vascular endothedial dysfunction for treatment of atherosclerosis using traditional Chinese medicine.Through the keywords of vasomotor

endothelial dysfunction

atherosclerosis

etc.thirty eight literature introducing the relationship between endothelial dysfunction and atherosclerosis

and summing up the research progress of treatment of endothelial dysfunction in the recent decade was collected and reviewed.The methods of treating atherosclerosis through regulating vascular endothelial dysfunction were summarized generally as the complementary therapy of natural substances for restoration of endothelial function

endothelial plantation and gene therapy

exogenous nitric oxide（NO）

endothelin antagonists

etc.;the progress on treating atherosclerosis through regulating NO and endothelin（ET） using Chinese single herb and formulas was presented.The results show that the methods of regulating the vascular endothelial dysfunction were diversified

the further study on the relationship between atherosclerosis and vasomotor substances such as NO/ET is the important research direction.The traditional Chinese medicine has significant role in the protection of endothelial dysfunction andregulating the endothelial secretion of active substances

but it lacks the depth on the material basis and mechanism that regulating vascular dysfunction

efficacy

so it will has broad prospects in the fields of preventing and treating cardiovascular disease to further explore the anti-atherosclerotic mechanisms of traditional Chinese medicine

playing the advantages of multi-target regulation of Chinese herbal compound

developing the anti-atherosclerosis traditional Chinese medicine based on the regulation of vascular dysfunction.