- 1.
BRAY F, LAVERSANNE M, SUNG H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2024, 74(3): 229-263.
- 2.
ZHENG R S, CHEN R, HAN B F, et al. Cancer incidence and mortality in China, 2022[J]. Chin J Oncol, 2024, 46(3): 221-231.
- 3.
LV T, LI Z, WANG D, et al. Role of exosomes in prostate cancer bone metastasis[J]. Arch Biochem Biophys, 2023, 748: 109784.
- 4.
ZHANG Y, MING A, WANG J, et al. PROTACs targeting androgen receptor signaling: Potential therapeutic agents for castration-resistant prostate cancer[J]. Pharmacol Res, 2024, 205: 107234.
- 5.
NOLSOE A B, JENSEN C, OSTERGREN P B, et al. Neglected side effects to curative prostate cancer treatments[J]. Int J Impot Res, 2021, 33(4): 428-438.
- 6.
GAI P, LI N, LIU M. Effect of combining traditional Chinese medicine with hormonal therapy on quality of life and tumor markers of prostate cancer patients[J]. Evid Based Complement Alternat Med, 2021: 5061867.
- 7.
ZHANG Y, WEI Y, JIANG S, et al. Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling[J]. Phytomedicine, 2022, 99: 153939.
- 8.
KAZMI I, ALTAMIMI A, AFZAL M, et al. The emerging role of non-coding RNAs in the Wnt/beta-catenin signaling pathway in prostate cancer[J]. Pathol Res Pract, 2024, 254: 155134.
- 9.
CHENG J, HUO D, ZHANG Z, et al. WDR1 promotes prostate cancer progression through Wnt/beta-catenin signaling[J]. Med Oncol, 2024, 41(6): 151.
- 10.
SONG P, GAO Z, BAO Y, et al. Wnt/beta-catenin signaling pathway in carcinogenesis and cancer therapy[J]. J Hematol Oncol, 2024, 17(1): 46.
- 11.
HU L, CHEN W, QIAN A, et al. Wnt/beta-catenin signaling components and mechanisms in bone formation, homeostasis, and disease[J]. Bone Res, 2024, 12(1): 39.
- 12.
SHARMA A, MIR R, GALANDE S. Epigenetic regulation of the Wnt/beta-catenin signaling pathway in cancer[J]. Front Genet, 2021, 12: 681053.
- 13.
LIU J, XIAO Q, XIAO J, et al. Wnt/beta-catenin signalling: Function, biological mechanisms, and therapeutic opportunities[J]. Signal Transduct Target Ther, 2022, 7(1): 3.
- 14.
KAPLAN Z, ZIELSKE S P, IBRAHIM K G, et al. Wnt and beta-catenin signaling in the bone metastasis of prostate cancer[J]. Life (Basel), 2021, 11(10): 1099.
- 15.
LOSADA-GARCIA A, SALIDO-GUADARRAMA I, CORTES-RAMIREZ S A, et al. SFRP1 induces a stem cell phenotype in prostate cancer cells[J]. Front Cell Dev Biol, 2023, 11: 1096923.
- 16.
YU W, SRIVASTAVA R, SRIVASTAVA S, et al. Oncogenic role of SATB2 in vitro: Regulator of pluripotency, self-renewal, and epithelial-mesenchymal transition in prostate cancer[J]. Cells, 2024, 13(11): 962.
- 17.
TERRISSE S, GOUBET A G, UEDA K, et al. Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer[J]. J Immunother Cancer, 2022, 10(3): e004191.
- 18.
TAN H, XIE Y, ZHANG X, et al. Integrative analysis of MALT1 as a potential therapeutic target for prostate cancer and its immunological role in pan-cancer[J]. Front Mol Biosci, 2021, 8: 714906.
- 19.
WANG C, CHEN Q, XU H. Wnt/beta-catenin signal transduction pathway in prostate cancer and associated drug resistance[J]. Discov Oncol, 2021, 12(1): 40.
- 20.
YANG D, YANG B, ZHU Y, et al. Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/Cyclin D1 axis[J]. Cancer Cell Int, 2021, 21(1): 379.
- 21.
HUSHMANDI K, SAADAT S H, RAEI M, et al. Implications of c-Myc in the pathogenesis and treatment efficacy of urological cancers[J]. Pathol Res Pract, 2024, 259: 155381.
- 22.
KOISTINEN H, KOVANEN R M, HOLLENBERG M D, et al. The roles of proteases in prostate cancer[J]. IUBMB Life, 2023, 75(6): 493-513.
- 23.
ZHANG B, ZHAO J, KANG D, et al. Flubendazole suppresses VEGF-induced angiogenesis in HUVECs and exerts antitumor effects in PC-3 cells[J]. Chem Biol Drug Des, 2024, 103(3): e14503.
- 24.
CHENG H, LI X, WANG C, et al. Inhibition of tankyrase by a novel small molecule significantly attenuates prostate cancer cell proliferation[J]. Cancer Lett, 2019, 443: 80-90.
- 25.
ZUO X, LIN H, SONG Z, et al. Antitumor activity of dictamnine against colorectal cancer through induction of ferroptosis and inhibition of M2 macrophage polarization via the MAPK signaling[J]. Arch Biochem Biophys, 2024, 758: 110051.
- 26.
LIAO Z W, LIANG C Y, CHEN C W, et al. Effect of dictamnine on inhibition of PC-3 cells with bone metastasis from prostate cancer via Wnt/beta-catenin signaling pathway[J]. J Pract Med, 2021, 37(3): 298-303.
- 27.
RADHAKRISHNA G K, AMMUNJE D N, KUNJIAPPAN S, et al. A comprehensive review of capsaicin and its role in cancer prevention and treatment[J]. Drug Res (Stuttg), 2024, 74(5): 195-207.
- 28.
CHEN H. Based on the effects of Wnt/β-catenin pathway capsaicin on prostate cancer PC-3 cells in vitro and in vivo[D]. Nanjing: Nanjing University of Chinese Medicine, 2022.
- 29.
CUI Y, ZHOU Q, JIN M, et al. Research progress on pharmacological effects and bioavailability of berberine[J]. Naunyn Schmiedebergs Arch Pharmacol, 2024, doi: .
- 30.
LU W, LIAN J H, WANG X R, et al. Exploring the effect of berberine on proliferation and apoptosis of prostate cancer cells based on Wnt/β-catenin protein signaling pathway[J]. Chin Comm Doc, 2022, 38(35): 12-14.
- 31.
JI E H, XU J, WEI J Y, et al. Research progress of active constituents and pharmacological effect of Moringa oleifera leaves[J]. Chin J Exp Tradit Med Form, 2021, 27(5): 214-223.
- 32.
XIE J, LUO F X, SHI C Y, et al. Moringa oleifera alkaloids inhibited PC3 cells growth and migration through the COX-2 mediated Wnt/beta-catenin signaling pathway[J]. Front Pharmacol, 2020, 11: 523962.
- 33.
SALARI N, FARAJI F, JAFARPOUR S, et al. Anti-cancer activity of chrysin in cancer therapy: A systematic review[J]. Indian J Surg Oncol, 2022, 13(4): 681-690.
- 34.
LIN Q, ZHANG X S, LIU S X, et al. Effect of chrysin regulating Wnt/β-catenin pathway on invasion and migration of prostate cancer cell line PC-3[J]. J New Chin Med, 2020, 52(18): 9-13.
- 35.
LIU F Y, DING D N, WANG Y R, et al. Icariin as a potential anticancer agent: A review of its biological effects on various cancers[J]. Front Pharmacol, 2023, 14: 1216363.
- 36.
LI L, WU H B, XING W Z. Icariin regulates proliferation and apoptosis of human prostate cancer cells through Wnt/β-catenin signaling pathway[J]. Pract J Cancer, 2023, 38(12): 1935-1939.
- 37.
ALRUMAIHI F, ALMATROODI S A, ALHARBI H, et al. Pharmacological potential of kaempferol, a flavonoid in the management of pathogenesis via modulation of inflammation and other biological activities[J]. Molecules, 2024, 29(9): 2007.
- 38.
QU X X, KONG D B, LU X H, et al. Effects and mechanism of kaempferol on T cell of prostate cancer mice by
- 39.
SHEIKHNIA F, FAZILAT A, RASHIDI V, et al. Exploring the therapeutic potential of quercetin in cancer treatment: Targeting long non-coding RNAs[J]. Pathol Res Pract, 2024, 260: 155374.
- 40.
ZHANG Z H, BAI J X. Anti-proliferation effect of quereetin on human prostate cancer PC-3 cells and Wnt /β-catenin signaling pathway[J]. Chin J Exp Tradit Med Form, 2016, 22(16): 144-148.
- 41.
BARUAH M M, KHANDWEKAR A P, SHARMA N. Quercetin modulates Wnt signaling components in prostate cancer cell line by inhibiting cell viability, migration, and metastases[J]. Tumour Biol, 2016, 37(10): 14025-14034.
- 42.
HE Y, YANG X, ZOU A Q, et al. Effects of quercetin-regulated G3BPl on migration, invasion and epithelial mesenchymal transition of prostate cancer cells via Wnt/β-catenin signaling pathway[J]. J Mod Urol, 2022, 27 (1): 60-65.
- 43.
SHARMA N, RAUT P W, BARUAH M M, et al. Combination of quercetin and 2-methoxyestradiol inhibits epithelial-mesenchymal transition in PC-3 cell line via Wnt signaling pathway[J]. Future Sci OA, 2021, 7(9): FSO747.
- 44.
WANG Q, WEI H C, ZHOU S J, et al. Hyperoside: A review on its sources, biological activities, and molecular mechanisms[J]. Phytother Res, 2022, 36(7): 2779-2802.
- 45.
CHEN J, ZHAO Y, WANG X, et al. Hyperoside inhibits RNF8-mediated nuclear translocation of beta-catenin to repress PD-L1 expression and prostate cancer[J]. Anticancer Agents Med Chem, 2024, 24(6): 464-476.
- 46.
TULI H S, RATH P, CHAUHAN A, et al. Phloretin, as a potent anticancer compound: From chemistry to cellular interactions[J]. Molecules, 2022, 27(24): 8819.
- 47.
KIM U, KIM C Y, LEE J M, et al. Phloretin inhibits the human prostate cancer cells through the generation of reactive oxygen species[J]. Pathol Oncol Res, 2020, 26(2): 977-984.
- 48.
BAILLY C. The subgroup of 2′-hydroxy-flavonoids: Molecular diversity, mechanism of action, and anticancer properties[J]. Bioorg Med Chem, 2021, 32: 116001.
- 49.
WU S, HUANG J, HUI K, et al. 2′‑Hydroxyflavanone inhibits epithelial‑mesenchymal transition, and cell migration and invasion via suppression of the Wnt/beta‑catenin signaling pathway in prostate cancer[J]. Oncol Rep, 2018, 40(5): 2836-2843.
- 50.
HUSAIN A, CHANANA H, KHAN S A, et al. Chemistry and pharmacological actions of delphinidin, a dietary purple pigment in anthocyanidin and anthocyanin forms[J]. Front Nutr, 2022, 9: 746881.
- 51.
LEE W, YUN J M. Suppression of beta-catenin signaling pathway in human prostate cancer PC3 cells by delphinidin[J]. J Cancer Prev, 2016, 21(2): 110-114.
- 52.
LU W, LIN C, LI Y. Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/beta-catenin and mTORC1 signaling in prostate and breast cancer cells[J]. Cell Signal, 2014, 26(6): 1303-1309.
- 53.
LI X, YUAN Z, WANG Y, et al. Recent advances of honokiol:Pharmacological activities, manmade derivatives and structure-activity relationship[J]. Eur J Med Chem, 2024, 272: 116471.
- 54.
ZHU Y H, XIONG J R, ZHANG T. Honokiol inhibits epithelial-mesenchymal transition process of prostate cancer cells by reducing activities of Wnt/β-catenin signaling pathway[J]. J Clin Pathol Res, 2020, 40(5): 1079- 1086.
- 55.
EL M N, ELOUAFY Y, MOUBACHIR R, et al. Chemistry, biological activities, and pharmacological properties of gastrodin: Mechanism insights[J]. Chem Biodivers, 2024, 21(6): e202400402.
- 56.
LIU Y M, WU A D, CHEN Y, et al. Gastrodin inhibits prostate cancer proliferation by targeting canonical Wnt/beta-catenin signaling pathway[J]. Med Oncol, 2023, 41(1): 32.
- 57.
LI T S, XI Z W, DONG W J, et al. Curcumin induces cycle arrest of colon cancer HCT116 cells via JAK1/STAT1/p21 pathway[J]. Chin J Exp Tradit Med Form, 2024, 30(9): 74-82.
- 58.
TEITEN M H, GAASCHT F, CRONAUER M, et al. Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway[J]. Int J Oncol, 2011, 38(3): 603-611.
- 59.
ALI M A, KHAN N, ALI A, et al. Oridonin from Rabdosia rubescens: An emerging potential in cancer therapy - A comprehensive review[J]. Food Sci Nutr, 2024, 12(5): 3046-3067.
- 60.
ZHANG S, VIJAYALAKSHMI A, MENG L. Oridonin attenuated human PC-3 cell activity by modulating the Wnt/beta-catenin signaling[J]. Adv Clin Exp Med, 2024, 33(5): 511-518.
- 61.
PAPARELLA A, SHALTIEL-HARPAZA L, IBDAH M. beta-ionone: Its occurrence and biological function and metabolic engineering[J]. Plants (Basel), 2021, 10(4): 754.
- 62.
FANG Q, QUE T, LIU B, et al. beta-ionone inhibits epithelial-mesenchymal transition (EMT) in prostate cancer cells by negatively regulating the Wnt/beta-catenin pathway[J]. Front Biosci :Landmark Ed, 2022, 27(12): 335.
- 63.
MAURYA S K, FATMA H, MAURYA A K, et al. Role of lupeol in chemosensitizing therapy-resistant prostate cancer cells by targeting MYC, beta-catenin and c-FLIP: In silico and in vitro studies[J]. In Silico Pharmacol, 2022, 10(1): 16.
- 64.
DOS S M C, SANTOS T B, FREITAS R, et al. Juglone: A versatile natural platform for obtaining new bioactive compounds[J]. Curr Top Med Chem, 2021, 21(22): 2018-2045.
- 65.
ZHAO L Z, CUI J B, MA J, et al. Juglone inhibits epithelial-mesenchymal transition of prostate cancer cells by regulating Wnt/β-catenin /Snail signaling pathway[J]. Chin J Pathophysiol, 2018, 34(10): 1910- 1913.
- 66.
YAO N, WANG C Y, ZHAO X T, et al. Effect of aloe-emodin on Aβ42 aggregation and cytotoxicity in presence of Al3+[J]. Chin J Exp Tradit Med Form, 2022, 28(18): 99-107.
- 67.
HUSSAIN T, ALAFNAN A, ALMAZNI I A, et al. Aloe-emodin exhibits growth-suppressive effects on androgen-independent human prostate cancer DU145 cells via inhibiting the Wnt/beta-catenin signaling pathway: An in vitro and in silico study[J]. Front Pharmacol, 2023, 14: 1325184.
- 68.
HUANG T, ZHAO C C, XUE M, et al. Current progress and outlook for agrimonolide: A promising bioactive compound from Agrimonia pilosa Ledeb[J]. Pharmaceuticals (Basel), 2023, 16(2): 150.
- 69.
NIE W D, JIA M R, SHAO Y Q, et al. Inhibition of prostate cancer cell proliferation and invasion by agrimonolide via the Wnt/β-catenin signaling pathway[J]. Mod Oncol, 2024, 32(4): 589-595.
- 70.
STURARO G, TASSO A, MENILLI L, et al. 4,6,4'-trimethylangelicin photoactivated by blue light might represent an interesting option for photochemotherapy of non-invasive bladder carcinoma: An in vitro study on T24 cells[J]. Biomolecules, 2021, 11(2): 158.
- 71.
MIOLO G, STURARO G, CIGOLINI G, et al. 4,6,4′-Trimethylangelicin shows high anti-proliferative activity on DU145 cells under both UVA and blue light[J]. Cell Prolif, 2018, 51(2): e12430.
- 72.
CHU Y, YUAN Q, JIANG H, et al. A comprehensive review of the anticancer effects of decursin[J]. Front Pharmacol, 2024, doi: .
- 73.
SONG G Y, LEE J H, CHO M, et al. Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin[J]. Mol Pharmacol, 2007, 72(6): 1599-1606.
- 74.
ZUO L, LI Y T, XIANG L B, et al. Computer-aided drug design and experimental validation reveal molecular mechanism of saikosaponin D-induced apoptosis of bladder cancer cells[J]. Chin J Exp Tradit Med Form, 2024, 30(17): 87-94.
- 75.
ZHONG D, ZHANG H J, JIANG Y D, et al. Saikosaponin-d: A potential chemotherapeutics in castration resistant prostate cancer by suppressing cancer metastases and cancer stem cell phenotypes[J]. Biochem Biophys Res Commun, 2016, 474(4): 722-729.
- 76.
WANG X, SU G Y, ZHAO C, et al. Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells[J]. J Ginseng Res, 2018, 42(2): 133-143.
- 77.
YANG S, XIAO H, SUN Y, et al. Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3beta and Fanconi anaemia pathway[J]. Phytother Res, 2021, 35(10): 5899-5918.
- 78.
ZENG S, ZHU B, ZENG J, et al. Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/beta‑catenin pathway[J]. Mol Med Rep, 2018, 18(6): 5572-5578.
- 79.
YU H, ZHANG Q, FAROOQI A A, et al. Opportunities and challenges of fucoidan for tumors therapy[J]. Carbohydr Polym, 2024, 324: 121555.
- 80.
BOO H J, HONG J Y, KIM S C, et al. The anticancer effect of fucoidan in PC-3 prostate cancer cells[J]. Mar Drugs, 2013, 11(8): 2982-2999.
- 81.
TANG Q, WU Q, SONG Q Y, et al. Exploring the effects and mechanisms of lutein on the proliferation and migration of human prostate cancer cells based on the Wnt/β-catenin signaling pathway[J]. Chin J Gerontol, 2024, 44(12): 2994-2998.
- 82.
ZHENG L, JIANG H, ZHANG Z W, et al. Arsenic trioxide inhibits viability and induces apoptosis through reactivating the Wnt inhibitor secreted frizzled related protein-1 in prostate cancer cells[J]. Onco Targets Ther, 2016, 9: 885-894.
- 83.
KIM D H, IM E, LEE D Y, et al. Antitumor mechanism of combination of Angelica gigas and Torilis japonica in LNCaP prostate cancer cells via G1 arrest and inhibition of Wnt/beta-catenin and androgen receptor signaling[J]. Phytother Res, 2022, 36(7): 2999-3008.
- 84.
LIU D G, LI Z R, ZHAO J, et al. Molecular mechanism of Yishen Tonglong decoction in treatment of prostate cancer: An exploration based on network pharmacology and molecular docking[J]. Pharmacol Clin Chin Mater Med, 2021, 37(5): 146-154.
- 85.
ZHU W X, YUAN Y F, PENG T, et al. Interventional effects of Yishen Tonglong granules on regulating the Wnt/β-catenin signaling pathway in nude mice bearing human prostate cancer cell PC3 tumor[J]. J Hunan Univ Chin Med, 2023, 43(12): 2177-2184.
- 86.
CHEN H R, FANG S P, ZHANG D, et al. Study on Guben Qingyuan prescription combined with androgen deprivation therapy to control castration-resistant prostate cancer based on Wnt pathway of cancer stem cells[J]. Chin Arch Tradit Chin Med, 2023, 42(3): 111-115.
- 87.
WANG P Y, HUANG Q, WANG S D, et al. Interpretation of the key points of "Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries"[J]. Chin J Clin Thoracic Cardiovas Surg, 2024, 31(7): 933-954.
- 88.
CHEN C, HUANG R, WANG N, et al. Fu-Zheng-Yi-Liu Formula inhibits the stem cells and metastasis of prostate cancer via tumor-associated macrophages/C-C motif chemokine ligand 5 pathway in tumor microenvironment[J]. Chin J Nat Med, 2024, 22(6): 501-514.