Pathogenesis of Chronic Heart Failure with Anxiety and Depression and Therapeutic Mechanisms of Bupleuri Radix-based Formulas from Theory of Shaoyang Pivot

  • role: First author第一作者
  • Affiliation:

    School of Traditional Chinese Medicine(TCM), Hunan University of Chinese Medicine, Changsha 410208, China

    Institute of Basic TCM, Hunan Academy of Chinese Medicine, Changsha 410013, China

  • Email:386441851@qq.com
  • Introduction:谭朵廷,在读博士,从事中医基础理论研究,E-mail:386441851@qq.com
TAN Duoting12,  
  • Affiliation:

    School of Traditional Chinese Medicine(TCM), Hunan University of Chinese Medicine, Changsha 410208, China

    Institute of Diagnostics of TCM, Hunan University of Chinese Medicine, Changsha 410208, China

LIAN Kun13,  
  • Affiliation:

    School of Traditional Chinese Medicine(TCM), Hunan University of Chinese Medicine, Changsha 410208, China

    Institute of Diagnostics of TCM, Hunan University of Chinese Medicine, Changsha 410208, China

LIANG Hao13,  
  • Affiliation:

    School of Traditional Chinese Medicine(TCM), Hunan University of Chinese Medicine, Changsha 410208, China

    Institute of Diagnostics of TCM, Hunan University of Chinese Medicine, Changsha 410208, China

MENG Lichong13,  
  • role: Corresponding author通信作者
  • Affiliation:

    School of Traditional Chinese Medicine(TCM), Hunan University of Chinese Medicine, Changsha 410208, China

    Institute of Diagnostics of TCM, Hunan University of Chinese Medicine, Changsha 410208, China

  • Email:515800272@qq.com
  • Introduction:胡志希,博士,教授,从事心血管疾病证候本质与诊治规律研究,E-mail:515800272@qq.com
HU Zhixi13*

ملخص

القصور القلبي المزمن المصاحب للاكتئاب والقلق ينتمي إلى فئة "الأمراض القلبية المزدوجة" ؛ وقد اكتشف البحث أن القلق والاكتئاب مرتبطان ارتباطًا وثيقًا بخطر حدوث حوادث القلب وارتفاع معدل الوفيات لدى مرضى القصور القلبي. ويؤدي آلية المرض المعقدة إلى مواجهة تحديات في العلاج الطبي الحديث بتقديم قدرات علاجية محدودة وتفاعلات ضارة. يعتبر نظرية شُعبة الشمس القليلة بمثابة المركز لتوضيح الآلية المرضية الهامة لإضرار شُعبة الشمس القليلة وقلة إدارة الغازات، واضطراب التمثيل السائلي، ونقص النيران في الكبد وهو أمر هام في ظروف قصور القلب المصاحبة للاكتئاب والقلق. ووفقًا لمعالجة شُعبة الشمس القليلة الكلاسيكية - الوصفات البحرية بالآذان (شوربة العشار، شوربة الحزاز القرنفلي، شوربة الحزاز بالعظم) عن طريق علاج شُعبة الشمس، فإنه يمكن أن يحقق أعادة توازن تمثيل الغاز، ونفاذي الشمس واستغلال نارية الصفتين، وتحسين حالة الاكتئاب المصاحب للقصور القلب، وهو يعتمد على قراءة معارف الشفاء المزدوجة وفعاليتها. أظهرت الدراسات الفعلية أن الوصفات البحرية بالآذان لها تأثيرات عدة في نقاط التأثير العصبية، وتثبيط تفاعل الالتهاب، وتنظيم الاستقلاب الدهني، وحماية الخلايا العضلية القلبية، وتحسين وظيفة البطانة الداخلية، وقدم هذا البحث تصورا عن آلية شُعبة الشمس القليلة لتوضيح الآليات المرضية للقصور القلب والاكتئاب والقلق وتفحص الآليات الفعالية للوصفات بالآذان بالدوائي. يقدم هذا البحث انطباعا مفصلاً حول الآليات الطبية لشُعبة الشمس القليلة وتأثيراتها وكونه قاعدة نظرية لقصور القلب والاكتئاب والقلق، ويعمق في تحليل الآليات دوائية الوصفات بالآذان لتحسين علاج قصور القلب والاكتئاب والقلق.

مفهوم

Shaoyang Pivot;psycho-cardiological disease;chronic heart failure;state of anxiety and depression;Bupleuri Radix-based formulas

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