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Optimisation de la méthode de calibrage des paramètres de modélisation des éléments discrets de poudre à base de plantes dans des conditions de faible cisaillement

  • role： First author第一作者
  • Affiliation：

    Beijing Key Laboratory for Production Process Control and Quality Evaluation of Chinese Medicine，Beijing University of Chinese Medicine，Beijing 102400，China

  • Email：tangxuefang_0821@163.com
  • Introduction：唐雪芳，在读硕士，从事中药制药过程仿真研究，E-mail：tangxuefang_0821@163.com
TANG Xuefang1,  
  • Affiliation：

    State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture，Nanjing University of Chinese Medicine，Nanjing 210023，China

    Jiangsu Kanion Pharmaceutical Co. Ltd.，Lianyungang 222001，China

LI Huanzheng23,  
  • Affiliation：

    Beijing Key Laboratory for Production Process Control and Quality Evaluation of Chinese Medicine，Beijing University of Chinese Medicine，Beijing 102400，China

LIANG Zichen1,  
  • Affiliation：

    Beijing Key Laboratory for Production Process Control and Quality Evaluation of Chinese Medicine，Beijing University of Chinese Medicine，Beijing 102400，China

LIU Yifei1,  
  • Affiliation：

    Beijing Key Laboratory for Production Process Control and Quality Evaluation of Chinese Medicine，Beijing University of Chinese Medicine，Beijing 102400，China

LIU Ying1,  
  • role： Corresponding author通信作者
  • Affiliation：

    State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture，Nanjing University of Chinese Medicine，Nanjing 210023，China

    Jiangsu Kanion Pharmaceutical Co. Ltd.，Lianyungang 222001，China

  • Email：879164331@qq.com
  • Introduction：徐芳芳，博士，主管药师，从事中药制药过程新技术研究，E-mail：879164331@qq.com
XU Fangfang23*,  
  • role： Corresponding author通信作者
  • Affiliation：

    Beijing Key Laboratory for Production Process Control and Quality Evaluation of Chinese Medicine，Beijing University of Chinese Medicine，Beijing 102400，China

  • Email：xubing@bucm.edu.cn
  • Introduction：徐冰，博士，教授，博士生导师，从事中药智能制药工程学研究，E-mail：xubing@bucm.edu.cn； *
XU Bing1*

résumé

L'objectif de cette étude est d'améliorer la précision de la modélisation des processus de traitement de poudre à base de plantes dans des conditions de faible cisaillement en utilisant la méthode des éléments discrets. Toutes les hypothèses ont été testées avec succès, ce qui fournit un soutien plus solide à la précision de la simulation.

mots-clés

méthode des éléments discrets; angle de repos; angle de frottement interne efficace; calibrage des paramètres; paramètres de contact clés; faible cisaillement; optimisation de la surface de réponse

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