References

1. 1.
   PENG W.Study on the compatibility relationship of classic prescription Sini decoction in the "drug-organism-efficacy" linkage link［D］.Chengdu：Chengdu University of Traditional Chinese Medicine，2023.
2. 2.
   ZHANG J M，LIAO W，HE Y X，et al.Study on intestinal absorption and pharmacokinetic characterization of diester diterpenoid alkaloids in precipitation derived from Fuzi-Gancao herb-pair decoction for its potential interaction mechanism investigation［J］.J Ethnopharmacol，2013，147（1）：128-135.
3. 3.
   PETER K，SCHINNERL J，FELSINGER S，et al.A novel concept for detoxification：Complexation between aconitine and liquiritin in a Chinese herbal formula（"Sini Tang"）［J］.J Ethnopharmacol，2013，149（2）：562-569.
4. 4.
   TIAN X H，ZHANG H，LI T，et al.New strategy on scientific connotation of Chinese materia medica compatibility enlightened by precipitation from Chinese materia medica formula decoction［J］.Chin Tradit Herb Drugs，2017，48（22）：4778-4783.
5. 5.
   ZHANG J M.Study on the compatibility mechanism between Radix Aconiti Lateralis and Radix Glycyrrhizae for toxicity reduction based on the effect link that toxic and effective consistutites deposit in vitro and sustained-release in vivo［D］.Chengdu：Chengdu University of Traditional Chinese Medicine，2012.
6. 6.
   CHEN J P，TAN B Y，WU W K，et al.Study on the compatibility of aconite and licorice in Sini decoction［J］.Chin J Exp Tradit Med Form，2001，7（3）：16-17.
7. 7.
   YANG H R，SUN J N，ZHANG G P，et al.Study on the effect and toxicity of Sini decoction formula from the different compatibility prescription［J］.Chin J Exp Tradit Med Form，2013，19（23）：266-269.
8. 8.
   HU Q.Study on component analysis and effects on anti-atherosclerosis of traditional Chinese medicine "Sini decoction"［D］.Dalian：Dalian University of Technology，2022.
9. 9.
   HE C，LIU S Y，WANG M Y，et al.Pharmacokinetic differences of seven components in different phases of Banxia Xiexin decoction in rats［J］.Chin J Exp Tradit Med Form，2025，31（13）：215-222.
10. 10.
    LI Y，ZHANG H M，HE Y，et al.Optimization of preparation of Sini decoction［J］.Chin Tradit Pat Med，2013，35（6）：1175-1179.
11. 11.
    PEI M R，DUAN X J，PEI X P.Compatibility chemistry of acid-alkaline pair medicine of Fuzi and Gancao in Sini decoction［J］.China J Chin Mater Med，2009，34（16）：2047-2050.
12. 12.
    ZHANG H M，CUI B J.Application of conductivity measurement method in the extraction of effective components of traditional Chinese medicine［J］.Chin J Integr Med Cardio-Cerebrovasc Dis，2017，5（34）：16.
13. 13.
    LIU H X，SUN S Q，YANG J S.Study on the compatibility of medicines of Sini decoction by using fourier transform infrared spectroscopy［J］.Spectrosc Spect Anal，2007，27（7）：1316-1318.
14. 14.
    ZHANG J M，FU C M，HE Y X，et al.Comparison on chemical components in sediments of Aconiti Lateralis Radix Preparata-Glycyrrhizae Radix et Rhizoma before and after their compatibility［J］.Chin Tradit Herb Drugs，2013，44（2）：165-169.
15. 15.
    HUANG Z F，TANG X L，LUO H，et al.Chemical constituents of Aconite Lateralis Radix and changing regularities during decoction process by HPLC-Q-TOF-MS［J］.Chin J Exp Tradit Med Form，2015，21（1）：57-63.
16. 16.
    LI W，SONG Y G，LIU K Y，et al.Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MSE combining with metabonomics［J］.Acta Pharm Sin，2016，51（9）：1445-1450.
17. 17.
    LI S S，LI F，ZHANG J X，et al.Rapid identification of alkaloids component in Shaanxi-produced crudeaconite based on UHPLC-Q-Exactive focus-MS/MS technique［J］.Chin Arc Tradit Chin Med，2025，43（1）：231-240.
18. 18.
    YAN P F.Study on the differences in the composition of different medicinal parts of Zingiberis Rhizoma and its mechanismof action in the treatment of diarrhea［D］.Shijiazhuang：Hebei Medical University，2023.
19. 19.
    CHEN C，GENG J L，KUANG H X，et al.Study on variation of non-volatile compounds of Raw Ginger after processing by UHPLC-Orbitrap/HRMS［J］.J Nanjing Univ Tradit Chin Med，2020，36（3）：387-395.
20. 20.
    XU Y L，LI C X，YANG F X，et al.Identification of chemical constituents in the classical prescription Shaoyao Gancao decoction based on UHPLC-Q-Exactive Orbitrap MS［J］.J Nanjing Univ Tradit Chin Med，2021，37（6）：938-948.
21. 21.
    LOU H H.Study on effects and immune mechanism of Licorice and Rhizoma Zingiberis with "Xin Gan Hua Yang" in treating asthma of lung yang deficiency［D］.Jinan：Shandong University of Traditional Chinese Medicine，2022.
22. 22.
    ZHANG L，WANG Y，ZHANG C，et al.Analysis of chemical constituents in Daishenning by HPLC-Q-TOF-MS/MS［J］.Chin J Exp Tradit Med Form，2021，27（13）：137-145.
23. 23.
    ZHANG Q Y，DONG W M，WANG X H，et al.Analysis of the changes in chemical components of Gancao Ganjiang decoction before and after its compatibility by UPLC-LTQ-Orbitrap-MS［J］.Chin Tradit Pat Med，2023，45（1）：311-316.
24. 24.
    ZHANG J W，HUA J K，LI R S，et al.Material basis and its distribution in vivo of Qili Qiangxin capsules analyzed by UPLC-Q-Orbitrap-MS［J］.Chin J Exp Tradit Med Form，2025，31（5）：185-193.
25. 25.
    WEN T.Clinical observation and mechanism study of Chaihu Guizhi Ganjiang decoction in treating chronic non-atrophic gastritis with gallbladder heat and spleen cold syndrome［D］.Shanghai：Naval Medical University，2024.
26. 26.
    PENG W.Study of the effective components change rules and pharmacodynamic differences of Sini decoction before and after compatibilities［D］.Chengdu：Chengdu University Traditional Chinese Medicine，2015.
27. 27.
    LAN J，AIXIAMU X Y T，HE L P，et al.Influence on content and in vitro intestinal adsorption of aconite alkaloids in water decoction after compatibility of Radix Aconite Lateralis Preparata and baked Radix Glycyrrhizae［J］.J Chi Pharm Univ，2012，43（5）：430-434.
28. 28.
    YANG M，LIU X B，HUANG Q D.The increasing effect and reducing ill effect principe of compatibility of Radix Aconiti Laterlis Preparata and Radix Glycyrrhizae［J］.Lishizhen Med Mater Med Res，2003，14（4）：197-198.
29. 29.
    JIANG C L，SHEN Z L，LÜ M L，et al.Comparative study on the effective components of Sini decoction formula granules and traditional decoction［J］.West China J Pharm Sci，2023，38（2）：191-195.
30. 30.
    LIAN K，LI P Y，SONG Z G，et al.Cardiomyocyte apoptosis and Chinese medicine intervention in chronic heart failure［J］.Chin J Exp Tradit Med Form，2025，31（16）：165-172.
31. 31.
    HUANG X，ZHANG L J，MIAO M S，et al.Analysis of composition，mechanism，mechanisms，attenuated measures and evaluation methods.［J］.Chin J Exp Tradit Med Form，2025，31（11）：295-304.
32. 32.
    PENG W，LIU D M，FU S，et al.Metabolomics-based analysis of toxicity changes of Aconiti Lateralis Radix PraeparataZingiberis Rhizoma in Sinitang before and after compatibility［J］.Chin J Exp Tradit Med Form，2023，29（18）：126-136.
33. 33.
    LI W，YANG X Q，ZHANG J M，et al.Effect of Aconiti Lateralis Radix Praepareta combined with Glycyrrhizae Radix et Rhizoma on in situ intestinal absorption of alkaloids in Aconiti Lateralis Radix Praepareta［J］.Chin J Exp Tradit Med Form，2018，24（22）：11-16.
34. 34.
    PEI M R，XUAN C S，DUAN X J，et al.Studies on chemical structure of complexes compounds formed by acid and alkaline components of pair medicines in decoction［J］.China J Chin Mater Med，2009，34（23）：3054-3059.
35. 35.
    LI B J，SHEN Y，LIAO R T，et al.Investigating mechanism of toxicity reduction by combination of Glycyrrhizae Radix et Rhizoma and Aconiti Lateralis Radix Preparata on terms of proteins self-assembly［J］.China J Chin Mater Med，2015，40（4）：661-666.