厥陰病に基づく烏梅丸方の加減によるがん性疼痛の治療に関する考察

  • role: First author第一作者
  • Affiliation:

    Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053,China

  • Email:2772055219@qq.com
  • Introduction:刘海啸,在读硕士,从事经方治疗癌性疼痛的临床与基础研究,E-mail:2772055219@qq.com
LIU Haixiao1,  
  • Affiliation:

    Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053,China

    Beijing University of Chinese Medicine, Beijing 100029,China

MENG Linghan12,  
  • Affiliation:

    Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053,China

ZHENG Guangda1,  
  • Affiliation:

    Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053,China

LI Dongtao1,  
  • Affiliation:

    Liaoning University of Traditional Chinese Medicine, Shenyang 110847,China

SHANG Lu3,  
  • Affiliation:

    Liaoning University of Traditional Chinese Medicine, Shenyang 110847,China

REN Juanxia3,  
  • Affiliation:

    Liaoning University of Traditional Chinese Medicine, Shenyang 110847,China

LI Changlin3,  
  • Affiliation:

    Liaoning University of Traditional Chinese Medicine, Shenyang 110847,China

WANG Lingyun3,  
  • role: Corresponding author通信作者
  • Affiliation:

    Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053,China

  • Email:baoyanju@126.com
  • Introduction:鲍艳举,博士,主任医师,从事经方治疗癌性疼痛的临床与基础研究,E-mail:baoyanju@126.com
BAO Yanju1*

サマリー

痛みはがん患者に最も一般的な症状の一つであり、患者の生活の質に深刻な影響を及ぼします。現在臨床で使用されている三段階の鎮痛法では、がん患者の痛みを完全に緩和できず、多くの問題を伴います。本論文は中医学の厥陰病の視点から、がん痛の核心病機は「正虚」と「寒熱錯雑」であるとし、烏梅丸を主方とし、証に応じて加減し、上を清め下を温め、寒熱を調和させ、身体の「虚・寒・瘀・毒・熱」の病理環境を調整し、身体の「陽化気」「陰成形」の生理機能を回復させ、がん痛を予防、緩和、あるいは消除し、良好な臨床効果を得ました。これはがん患者の痛みを和らげるだけでなく、「腫瘍をコントロール」し「消失」させることも可能にし、痛みの緩和と腫瘍の制御という二重の効果を実現し、中医学の証に基づく治療の特色と利点を発揮し、張仲景の厥陰病脈証並治の範囲を拡大し、虚実混在、寒熱錯雑の観点からがん性疼痛の診断・治療に臨床上の示唆を提供します。

キーワード

がん性疼痛; 厥陰病; 烏梅丸; 中医学

References

  1. 1.
    National Health Commission of the People's Republic of China.Chinese society of clinical oncology.cancer pain diagnosis and treatment guidelines (2018 edition)[J].Chin Clin Oncol,2018,23(10):937-944.
  2. 2.
    TAN M L,CHENG C,WANG C M,et al.Research progress on pathogenesis and treatment of cancer pain[J].Anti Tumor Pharm,2022,12(1):6-11.
  3. 3.
    ZHU L J,DING Y,LIU J.Effect of pain nursing intervention on improving pain intensity in elderly cancer patients:Commentary on "Nursing Manual for Elderly Cancer Patients"[J].Chin J Exp Tradit Med Form,2023,29(22):170.
  4. 4.
    TE BOVELDT N ,VERNEOOIJ-DASSEN M,BURGER N,et al.Pain and its interference with daily activities in medical oncology outpatients[J].Pain Physician,2013,16(4):379-389.
  5. 5.
    SWARM R A,PAICE J A,ANGHELESCU D L,et al.Adult cancer pain,Version 3.2019,NCCN clinical practice guidelines in oncology[J].J Natl Compr Canc Netw,2019,17(8):977-1007.
  6. 6.
    WU L X,SUN L.Current situation and reasons for undertreatment of cancer pain[J].Cancer Res Prev Treat,2014,41(4):421-424.
  7. 7.
    WANG L Y,ZHENG G D,SHANG L,et al.Traditional Chinese medicine for cancer pain management:A review[J].Chin J Exp Tradit Med Form,2026,doi:.
  8. 8.
    LI Y Y,ZHENG H G,BAO Y J,et al.Treating cancer pain based on the core pathogenesis of blood stasis[J].Acta Chin Med,2021,36(11):2281-2284.
  9. 9.
    LI D T,ZHENG G D,BAO Y J,et al.HUA Baojin's experience in treating cancerous pain based on toxin-stasis theory[J].Chin J Tradit Chin Med Pharm,2024,39(8):4149-4152.
  10. 10.
    ZHENG G D,BAO Y J.Treatment of cancer pain from the perspective of deficiency-phlegm-stasis-toxin[J].Chin J Tradit Chin Med Pharm,2024,39(10):5313-5316.
  11. 11.
    ZHENG G D,TANG Y T,CHEN Y P,et al.Professor HUA Baojin's experience in treating cancer pain by regulating Qi and detoxifying[J].World Chin Med,2022,17(11):1511-1514.
  12. 12.
    ZHANG Z J.Treatise on cold damage disorders[M].Beijing:People's Medical Publishing House,2005:94
  13. 13.
    HU X S,FENG S L,HU X S Famous Research Office,et al.HU Xishu's lecture notes on treatise on cold damage[M].Beijing:China Press of Traditional Chinese Medicine,2023:389-391.
  14. 14.
    Essential Clinical Readings Reprint:Huangdi Neijing Suwen[M].Collated by TIAN D H.Beijing:People's Medical Publishing House,2023:154.
  15. 15.
    CHEN X Y.Changsha Formula Verses[M].Beijing:China Press of Traditional Chinese Medicine,2016:115.
  16. 16.
    LAI G H,WANG F,NIE D R,et al.Research progress on pathogenesis of bone metastasis cancer pain and prevention with traditional Chinese medicine[J].Chin J Exp Tradit Med Form,2023,29(11):231-239.
  17. 17.
    CHEN Y P,TANG Y T,BAO Y J.Treatment of cancer pain from the perspective of Jueyin disease[J].Global Tradit Chin Med,2021,14(4):711-713.
  18. 18.
    YU G C.Popular treatise on cold damage[M].Collated and annotated by CHEN B,ZHU J P.Beijing:China Press of Traditional Chinese Medicine,2022:31.
  19. 19.
    BAO Y J.Mechanism of Xiaozheng Zhitong topical formula regulating osteoclast activation and PAR2/TRPV1 signaling pathway in treating bone cancer pain[D].Beijing:China Academy of Chinese Medical Sciences,2015.
  20. 20.
    REN X L,BAO Y J,LIU R,et al.Experience in treating pulmonary nodules with modified Simiao pill[J].J Tradit Chin Med,2023,64(14):1504-1508.
  21. 21.
    ZUO B J,LIU L K.Professor LIU Likun's experience in treating adverse reactions in advanced cancer patients with Wumei pill[J].Asia-Pac Tradit Med,2019,15(12):95-97.
  22. 22.
    WANG Q G,ZHOU C X.Selected readings of treatise on cold damage[M].5th New Century Edition.Beijing:China Press of Traditional Chinese Medicine,2021:209.
  23. 23.
    KE Q.Collection of reviving treatise on cold damage[M].Beijing:China Medical Science Press,2011:175.
  24. 24.
    WANG X,ZHANG Y W.Essentials of classical formula Wumei pill in treating malignant tumors[J].Jiangsu J Tradit Chin Med,2022,54(3):50-53.
  25. 25.
    JI Y J,LI H X,LU W M.Clinical application of Wumei pill based on modern literature analysis[J].Shandong J Tradit Chin Med,2019,38(3):216-220.
  26. 26.
    LI P J,LIU L X,WANG Q,et al.Experience analysis of Wumei pill in treating cold-heat complex stage of malignant tumors[J].Liaoning J Tradit Chin Med,2021,48(1):153-155.
  27. 27.
    ZHENG Y P.Study on the formula pattern of Wumei pill based on ancient and modern literature[D].Beijing:China Academy of Chinese Medical Sciences,2021.
  28. 28.
    YAN S G,HUI Y,ZHOU Y X.Analgesic effect of Wumei pill and its disassembled prescriptions[J].Chin J Exp Tradit Med Form,2013,19(21):262-265.
  29. 29.
    Editorial Board of "Learning Chinese Medicine by Ear Series".Classic of Difficulties & Divine Farmer's Materia Medica[M].Beijing:China Press of Traditional Chinese Medicine,2010:91.
  30. 30.
    JIN H,PANG X Y,LIU X W,et al.Research progress of Wumei pill in treating malignant tumors[J].J Clin Med Pract,2021,25(8):129-132.
  31. 31.
    LIU Y F,AN T,YU H,et al.Pharmacological mechanism of Wumei pill in treating breast cancer with lung metastasis[J].Chin J Exp Tradit Med Form,2021,27(9):193-201.
  32. 32.
    XIA L,SU L,ZHANG M.Feasibility analysis of Wumei pill in treating advanced biliary tract malignant tumors[J].Chin J Exp Tradit Med Form,2021,27(1):229-234.
  33. 33.
    LI Z Z,QIAN Y Z,JIN Z J.Leigong Paozhi Yaoxing Jie[M].Beijing:China Press of Traditional Chinese Medicine,1998:54-55.
  34. 34.
    Department of Basic TCM Theory,Beijing University of Chinese Medicine.Vernacular explanation of synopsis of golden chazamber cold damage formulas[M].Beijing:People's Medical Publishing House,1973:1.

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