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二重指数モデルに基づく中薬吸湿動態特徴付けおよび応用研究の進展

  • role： First author第一作者
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

  • Email：2767209661@qq.com
  • Introduction：余艳婷，在读硕士，从事中药制剂研究，E-mail：2767209661@qq.com
YU Yanting1,  
  • Affiliation：

    Jiangxi Provincial Drug Certification and Evaluation Center，Nanchang 330046，China

XIONG Lei2,  
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

HE Yan1,  
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

    National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China

LIU Wei13,  
  • Affiliation：

    National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China

YANG Jing3,  
  • Affiliation：

    National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China

ZHANG Yao3,  
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

CHEN Jiali1,  
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

    National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China

LUO Xiaojian13,  
  • role： Corresponding author通信作者
  • Affiliation：

    Jiangxi University of Chinese Medicine，Nanchang 330004，China

    National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China

  • Email：rxy1014@163.com
  • Introduction：饶小勇，博士，教授，博士生导师，从事中药制剂研究，E-mail：rxy1014@163.com
RAO Xiaoyong13*

サマリー

吸湿研究は中薬において常に注目されている重要な課題であり、吸湿メカニズムの解明は製剤処方、工程最適化および保管条件の選択に重要な役割を果たす。吸湿モデルは中薬の吸湿メカニズムを特徴づける重要な手段であり、多様な種類が存在する。二重指数モデルは物質とエネルギー保存の法則およびフィックの第一拡散法則に基づき、中薬抽出物の物性特徴を反映した動的数学モデルである。近年、このモデルは異なる湿度環境下における中薬抽出物および固体製剤の動的吸湿挙動をシミュレーションするために広く用いられ、中薬の吸湿動態パラメータと物材特性との関連規則を明らかにし、中薬の吸湿挙動の特徴付けに新たな視点を提供している。本論文はこのモデルの中薬分野における応用進展を体系的に総説し、本モデルの長所と短所および直面する課題を分析し、他分野への応用動向を展望することで、中薬吸湿メカニズムの解明および中薬防湿技術研究の参考とし、また食品や高分子材料などへの展開応用の手がかりを提供することを目的とする。

キーワード

二重指数モデル;中薬;吸湿;動態モデル;抽出物;固体製剤

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