Шеньвэнчжу судуянь и его активные ингредиенты в лечении повреждения легких

  • role: First author第一作者
  • Affiliation:

    School of Health Science,Guangdong Pharmaceutical University,Guangzhou 510006,China

  • Email:2694543312@qq.com
  • Introduction:林晓洁,从事中药复方作用机制的研究,E-mail:2694543312@qq.com
LIN Xiaojie1,  
  • Affiliation:

    School of Health Science,Guangdong Pharmaceutical University,Guangzhou 510006,China

WEN Xianan1,  
  • Affiliation:

    School of Health Science,Guangdong Pharmaceutical University,Guangzhou 510006,China

ZENG Qiaolin1,  
  • Affiliation:

    College of Pharmacy,Guangzhou Health Science College,Guangzhou 510450,China

WANG Li2,  
  • Affiliation:

    School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China

ZHENG Yuanru3,  
  • role: Corresponding author通信作者
  • Affiliation:

    School of Health Science,Guangdong Pharmaceutical University,Guangzhou 510006,China

  • Email:zhaojie6389@163.com
  • Introduction:赵杰,博士,副教授,从事中药复方作用机制的研究,E-mail:zhaojie6389@163.com
ZHAO Jie1*

реферат

Острое повреждение легких (ALI) представляет собой распространенный и часто смертельный клинический синдром, характеризующийся постепенным развитием острой дыхательной недостаточности. В настоящее время лечение ALI в основном основано на лечении дыхательной поддержки и симптоматическом лечении, по-прежнему отсутствует специфичное и эффективное лекарственное лечение. Шеньвэнчжу судуянь - это традиционное китайское лекарственное средство, обладающее свойствами стечения жара и отравления, механизм действия включает в себя противовоспалительное, жаропонижающее, антимикробное, антивирусное, седативное действие и т. д. Этот препарат содержит множество флавоноидов, фенолов, терпенов с сильной фармакологической активностью, которые могут регулировать воспалительные реакции и окислительный стресс, поддерживать целостность альвеолярно-капиллярного барьера (ACB) в ALI путем подавления клеточной апоптоза, антимикробной инфекции и фиброза легких, между флавоноидами, действие кверцетина, мирцитина, байхинина и т. д. достаточно разнообразно, механизм действия сложен, такие как, кверцетин, мирцитин, байхинин и т. д., могут воздействовать на несколько важных мишеней, в том числе на передачу сигнала фактора активации транскрипции 3 (STAT-3), митоген-активированная протеинкиназа 3 (MAPK-3), через регуляцию сигнальных путей, таких как то�

ключеви́че слова́

Шеньвэнчжу судуянь; повреждение легких; острое повреждение легких; активные ингредиенты; механизм действия

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