предыдущий|следующий

Исследовательский прогресс в лечении болезни Альцгеймера китайской медициной

  • role： First author第一作者
  • Affiliation：

    School of Pharmacy， Jiangxi University of Chinese Medicine， Nanchang 330000， China

  • Email：3029288406@qq.com
  • Introduction：徐铮，在读硕士，从事中药学相关研究，E-mail：3029288406@qq.com
XU Zheng1,  
  • Affiliation：

    School of Pharmacy， Jiangxi University of Chinese Medicine， Nanchang 330000， China

    Jiangzhong Pharmaceutical Co. Ltd.， Nanchang 330000， China

TANG Yuan12,  
  • Affiliation：

    Jiangzhong Pharmaceutical Co. Ltd.， Nanchang 330000， China

QIU Fenglan2,  
  • role： Corresponding author通信作者
  • Affiliation：

    School of Pharmacy， Jiangxi University of Chinese Medicine， Nanchang 330000， China

    Jiangzhong Pharmaceutical Co. Ltd.， Nanchang 330000， China

  • Email：lyg@crjz.com
  • Introduction：李诒光，副教授，硕士生导师，从事中药化学与中药药理研究，E-mail：lyg@crjz.com
LI Yiguang12*,  
  • Affiliation：

    Jiangzhong Pharmaceutical Co. Ltd.， Nanchang 330000， China

YANG Lingyu2,  
  • role： Corresponding author通信作者
  • Affiliation：

    School of Pharmacy， Jiangxi University of Chinese Medicine， Nanchang 330000， China

  • Email：19960246@jxutcm.edu.cn
  • Introduction：陈杰，硕士，副教授，硕士生导师，从事中药化学与中药药理研究，E-mail：19960246@jxutcm.edu.cn； *
CHEN Jie1*

реферат

Болезнь Альцгеймера (AD) — это распространенный тип деменции, который в основном проявляется нарушениями когнитивного поведения и дефицитами обучения и памяти. Развитие AD привело к огромному экономическому бремени для общества и семей, однако точные причины заболевания до конца не выяснены. Доступные в настоящее время лекарства ограничены и часто сопровождаются серьезными побочными эффектами. Традиционная китайская медицина и ее экстракты являются, как правило, природными продуктами, обладающими многими путями действия и низкими побочными эффектами. Некоторые эксперименты показали, что традиционная китайская медицина имеет огромный потенциал в лечении и профилактике AD, например, Хуанлиань Цзеду Тан, Данггуй Шаояо Сан, Кайсин Сан, Лю Вэй Ди Хуань Вань, Буян Хуань У Тан, женьшень, хуанци, готонг, хуанлиань, чжи цзы, гинкго, даньшэнь, куркума и др., которые могут уменьшать отложение β-амилоидного белка, подавлять гиперфосфорилирование тау-белка, восстанавливать функцию митохондрий, улучшать окислительный стресс, подавлять нейровоспаление и апоптоз, восстанавливать функцию синапсов и улучшать кишечную микрофлору. В статье суммированы эффекты некоторых китайских лекарственных средств и их составных частей на AD, что предоставляет参考 для дальнейшего лечения AD традиционной китайской медициной.

ключеви́че слова́

болезнь Альцгеймера;традиционная китайская медицина;комплексные рецепты ТКМ;механизм действия;нейровоспаление;кишечная микрофлора

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