Characteristics of Traditional Chinese Medicine Syndromes in Patients with Concurrent Postmenopausal Osteoporosis and Knee Osteoarthritis

  • role: First author第一作者
  • Affiliation:

    Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China

  • Email:xinroberttcm@hotmail.com
  • Introduction:E-mailxinroberttcm@hotmail.com
CUI Xin1,  
  • Affiliation:

    Beijing Electric Power Hospital of State Grid Corporation of China, Beijing 100055, China

GAO Huaiwei2,  
  • Affiliation:

    Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China

LIANG Long3,  
  • Affiliation:

    Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China

CHEN Ming3,  
  • Affiliation:

    Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China

WANG Shangquan3,  
  • Affiliation:

    Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China

CHENG Ting3,  
  • Affiliation:

    Nanjing University of Chinese Medicine, Nanjing 210023, China

ZHANG Yili4,  
  • role: Corresponding author通信作者
  • Affiliation:

    Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China

  • Email:weixu.007@126.com
  • Introduction:E-mailweixu.007@126.com
WEI Xu3*,  
  • role: Corresponding author通信作者
  • Affiliation:

    Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China

  • Email:ktzu2018@163.com
  • Introduction:E-mailktzu2018@163.com
XIE Yanming1*

resumen

El objetivo de este estudio es analizar las características de los síntomas de la medicina tradicional china en pacientes con comorbilidad de osteoartritis de rodilla (KOA) y osteoporosis posmenopáusica (PMOP), para proporcionar una base científica para un diagnóstico y tratamiento preciso de este tipo de patologías comunes. Se analizaron las características de los pacientes PMOP y KOA mediante una encuesta transversal prospectiva y multicéntrica, y las características generales de los sujetos incluidos fueron analizadas estadísticamente utilizando Excel 2021. Las variables continuas se informaron utilizando x¯±s para los informes, las variables binarias se informaron en porcentaje, y se construyeron modelos de red complejos "enfermedad-síntomas-síntomas" de los sujetos utilizando software UCINET y Gephi para una exploración profunda de las características estructurales, la información sobre las conexiones entre los nodos y las matrices de adyacencia ponderadas obtenidas a través de UCINET y Python, y una presentación visual de las redes complejas a través del software Gephi. El estudio recopiló información sobre los síntomas de la medicina tradicional china y las características de 157 sujetos con comorbilidad PMOP y KOA en 12 hospitales chinos de medicina tradicional o centros de servicios clínicos de la comunidad, y se identificaron 4 síntomas principales de comorbilidad PMOP y KOA, incluyendo el déficit de calor de los riñones (47,13%), el déficit de hígado y riñones (36,94%), el déficit de calor del bazo y los riñones (8,92%), el déficit de los riñones yin y yang (7,01%) y 10 combinaciones de síntomas (con deficiencia de calor del bazo y los riñones, debilidad de sangre y energía, deficiencia de calor del bazo, frío y humedad como síntomas principales). Combinando estadísticas de frecuencia, resultados de análisis de redes complejas y conocimientos de teoría de la medicina tradicional china y pautas relacionadas, el estudio estableció las características generales de los síntomas corporales, el dolor, la inspección de la lengua, el pulso y la orina de los pacientes con comorbilidad PMOP y KOA. Conclusión. Los principales síntomas de comorbilidad PMOP y KOA podrían ser el déficit de calor de los riñones, el déficit de hígado y riñones, el déficit de calor del bazo y los riñones, el déficit de los riñones yin y yang, entre los cuales el déficit de calor de los riñones y el déficit de hígado y riñones son síntomas clave.

palabra clave

postmenopausal osteoporosis;comorbidity;syndrome characteristics;knee osteoarthritis

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