References
- 1.CHUNG S C,GEDEBORG R,NICHOLAS O,et al. Acute myocardial infarction:A comparison of short-term survival in national outcome registries in Sweden and the UK[J].Lancet,2014,383(9925):1305-1312.
- 2.The Writing Committee of the Report on Cardiovascular Health and Diseases in China.Key points interpretation of China Cardiovascular Health and Disease Report 2021[J].Chin J Cardiovascular Med,2022,27(4):305.
- 3.MENG X M,YUAN J H,ZHOU Z F,et al. Evaluation of time-dependent phenotypes of myocardial ischemia-reperfusion in mice[J].Aging(Albany NY),2023,15(19):10627-10639.
- 4.HU C C,WEI X,LIU J M,et al.Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Nav1.5 downregulation and ventricular arrhythmias[J].Mil Med Res,2022,9(1):58.
- 5.LAN Z,TUO P,GAO Y G,et al. Research progress in treatment of acute myocardial infarction with traditional Chinese medicine[J].J Snake,2023,35(2):259-261,279.
- 6.LIU Z M,LIU R X,et al.Understanding and experience of syndrome differentiation and treatment of coronary heart disease[J].Acta Med Sin,1994,9(3):46-49.
- 7.DENG C X,HE D Y,SUN W,et al.Clinical observation of Danlou Tongbi decoction in treating angina pectoris of coronary heart disease with phlegm-stasis obstructing collaterals syndrome[J].J Emerg Syndromes Tradit Chin Med,2023,32(1):104-107.
- 8.WU Y L.Theory of meridian diseases in traditional Chinese medicine and three-dimensional network system[J].J Tradit Chin Med,2003,44(6):407-409.
- 9.CHANG C C.Theory and experimental research on prevention and treatment of cardiac sub-meridian-microvessel lesions guided by the theory of communication and bio-transformation through meridians in the theory of meridian and collateral[D].Nanjing:Nanjing University of Chinese Medicine,2017.
- 10.ZHAO L,LI L,WEI H F,et al.Evolvement of learning and memory ability in hyperlipedemic rats with phlegm and blood stasis syndromes[J].Chin J Integr Med Cardio/Cerebrovasc Dis,2008,6(4):415-417.
- 11.YUAN Y,GAO Y X,ZHANG Q Y,et al.Construction and evaluation of a cerebral infarction Qi-Yin deficiency syndrome mouse model based on metabolomics[J].Chin J Exp Tradit Med Form,2025,doi:.
- 12.SHI Y L,GAO Y X,ZHANG Q Y,et al.Establishment and evaluation of a rat model with acute myocardial infarction in coronary heart disease and Qi-Yin deficiency syndrome induced by sleep deprivation combined with coronary artery ligation[J].Chin J Exp Tradit Med Form,2025,doi:.
- 13.LI G H,LUO B,LV Y X,et al.Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia-reperfusion injury[J].J Transl Med,2016,14(1):116.
- 14.CHEN J,YE C,HU X,et al.Serum metabolomics model and its metabolic characteristics in patients with different syndromes of dyslipidemia based on nuclear magnetic resonance[J].J Pharm Biomed Anal,2019,167:100-113.
- 15.SUN J Z,NIU X Y,HAN L H,et al.Experimental study on micro-syndrome differentiation indicators of phlegm-turbidity syndrome[J].Henan Tradit Chin Med,1996,21(2):21-22.
- 16.LI D,LI J,LIU Y,et al.Discussion on the modern biological basis of phlegm syndrome based on the basic theory of traditional Chinese medicine[J].Liaoning J Tradit Chin Med,2020,47(2):93-95.
- 17.FENG J,YAN K P,ZHU M J,et al.Meta-analysis of the therapeutic effect of Gualou Xiebai Banxia Tang combined with Xuefu Zhuyu Tang on coronary heart disease angina pectoris from the perspective of phlegm and blood stasis[J].Shaanxi J Tradit Chin Med,2021,42(3):393-397.
- 18.ZHANG Y K,HAN J B,WANG Q G,et al.Effect of Huatan Kaibi decoction on pre-thrombotic state and platelet aggregation rate in patients with coronary heart disease angina pectoris of phlegm-turbidity obstruction type[J].Chin J Integr Med Cardio,2022,20(10):1732-1735.
- 19.BUTLER M J,CHAN W,TAYLOR A J,et al.Management of the no-reflow phenomenon[J].Pharmacol Ther,2011,132(1):72-85.
- 20.CHEN C,WU D,LV X L,et al.Effect of electroacupuncture preconditioning on adhesion molecules and endothelial cell function in rats with no-reflow after acute myocardial infarction reperfusion[J].Mod J Integr Tradit Chin West Med,2019,28(19):2067-2071.
- 21.LI F Z.Correlation analysis of traditional Chinese medicine syndromes and objective indicators in different clinical types of coronary heart disease[D].Shenyang:Liaoning University of Traditional Chinese Medicine,2023.
- 22.MA C L,WANG Y G,ZHENG G.Overview of methods for establishing animal models of coronary heart disease with phlegm-stasis intermingled syndrome[J].Intern Med J Pract Tradit Chin Med,2015,29(11):179-181.
- 23.LI L,WANG A A,LIU Z X,et al.Research status and prospects of animal models of coronary heart disease with phlegm-stasis intermingled syndrome[J].Chin J Tradit Chin Med,2023,38(3):969-973.
- 24.REN J G,LIU J X,WEI J H.Disease-syndrome combined pharmacology:Strategy and method for the study of traditional Chinese medicine pharmacology[J].Chin J Tradit Chin Med,2021,46(19):4922-4929.
- 25.LI X Z.Pathological mechanism and foundation of formula-syndrome correspondence in a coronary heart disease model with phlegm-stasis intermingled syndrome[D].Beijing:China Academy of Chinese Medical Sciences,2008.
- 26.HE K,YAN L,LIN S Q,et al.Implication of IGF1R signaling in the protective effect of Astragaloside Ⅳ on ischemia and reperfusion-induced cardiac microvascular endothelial hyperpermeability[J].Phytomedicine,2022,100:154045.
- 27.LIU Z,HAN X,YOU Y,et al.Shuangshen ningxin formula attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial function[J].J Ethnopharmacol,2024,323:117690.
- 28.QIAN F.Study on the pathogenesis of phlegm-stasis obstructing collaterals syndrome in angina pectoris of coronary heart disease[J].J Jilin Tradit Chin Med,2008,28(4):241.
- 29.ZHAO X D,SHI J X.Mechanism and therapies of cerebralvasospasm following subarachnoid hemorrhage[J].J Med Postgraduates,2010,23(2):218-222.
- 30.LIU H,WANG H T.The changes of endothelin—A receptor mRNA in the cerebral basilartery of rats with subarachnoid hemorrhage[J].Shaanxi Med J,2009,38(4):402-404.
- 31.WÖLKART G,STESSER H,SAA D Z,et al.Cardioprotective effects of atrasentan,an endothelin-A receptor antagonist,but not of nitric oxide in diabetic mice with myocyte-specific overexpression of endothelial nitric oxide synthase[J].Br J Pharmacol,2006,148(5):671-681.
- 32.LIU W W,LIU M L.Research progress on the prevention of cardiovascular diseases by ω-3 polyunsaturated fatty acids[J].Chin J Cardiovasc Med,2018,23(6):510-514.
- 33.YUAN Q,XIE F,HUANG W,et al.The review of alpha-linolenic acid:Sources,metabolism,and pharmacology[J].Phytother Res,2022,36(1):164-188.
- 34.LAI J S,CHEN C.The roles of cytochrome P450 metabolites of arachidonic acid in the regulation of vascular function[J].Acta Physiol Sin,2021,73(4):631-645.
- 35.CHEN Q H.Relationship between arachidonic acid and atherosclerosis and thrombosis formation[J].Prog Physiol Sci,1983,27(2):112-117.
- 36.HU Y,LI W,CHENG X,et al.Emerging roles and therapeutic applications of arachidonic acid pathways in cardiometabolic diseases[J].Circ Res,2024,135(1):222-260.


