Comparative Studies on Different Proporations of Ingredients in Danggui Buxue Decoction

Jin Fang1; Sun Xiaoyan2

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Comparative Studies on Different Proporations of Ingredients in Danggui Buxue Decoction

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- Comparative Studies on Different Proporations of Ingredients in Danggui Buxue Decoction
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 1, Issue 1, Pages: 33-37(1995)
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  CLC： R259.313R285
- Published：1995
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Jin Fang1, Sun Xiaoyan2. Comparative Studies on Different Proporations of Ingredients in Danggui Buxue Decoction[J]. Chinese Journal of Experimental Traditional Medical Formulae, 1995, 1(1): 33-37.
DOI：

Jin Fang1, Sun Xiaoyan2. Comparative Studies on Different Proporations of Ingredients in Danggui Buxue Decoction[J]. Chinese Journal of Experimental Traditional Medical Formulae, 1995, 1(1): 33-37. DOI：

摘要

采用反相高效液相色谱法测定不同比例配伍的当归补血汤中阿魏酸的煎出率

并进一步观察了它们对小鼠吞噬功能和免疫器官的影响。结果表明;当归补血汤按经典的当归-黄芪(1:5)配伍时

阿魏酸的煎出率最高;并且当归-黄芪按1:5和5:1配伍时其阿魏酸的煎出率均明显高于按1:1配伍者。药理实验亦表明;当归-黄芪(1:5)配伍的当归补血汤提高小鼠廓清指数(K)和吞噬指数(α)的作用明显强于其它比例配伍者。

Abstract

Using reversal HPLC

yields of ferulic acid isolated from Danggui Buxue decoction(DBD)with various proporations of its two ingredients

Radix Angelicae Sinensis(RAS)and Radix Astragali(RAH)

were comparatively estimated.Furthermore

effects of extracts from DBD with different ingredient pro-porations on phagocytic function and immune organs were also explored in mice.The highest yield of ferulic acid was obtained when a classical ratio of RAS and RAH(1:5) in DBD was adopted.The yield of ferulic acid from DBD with a 1:5 or a 5:1 ratio between RAS and RAH was much higher than that with a 1:1 ratio of t he two ingredients. Pharmacological data showed that efficacy of in-creasing clearance index(K)and phagocytic index(α)by DBD with the 1:5 ratio of RAS and RAH was more potent than that by DBD with other ratios ofthe two ingredients.

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Related Author

Wang Hongjie1

Shen Xin1

Yang Jian1

Yang Hua1

Bian Baolin1

Guo Xulin2

LI Yuexin

ZHANG Zhijing

Related Institution

The First Affiliated Hospital of Zhengzhou University

School of Traditional Chinese Medicine （Zhongjing），Henan University of Chinese Medicine

Laboratory Animal Science and Technology Center，Jiangxi University of Chinese Medicine

National Key Laboratory of Modern Chinese Medicine Creation of Classic Prescriptions

Jiangxi University of Chinese Medicine，Key Laboratory of Modern Preparation of Traditional Chinese Medicine，Ministry of Education

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