A mucosa inflammation model was set up by either infecting Klebsiella pneumonia or dribbling 2

4-chloronitrobenzene in rat's nasal cavity. Pathological examination confirmed that nasal vestibule appeared to be hyperplasia of squamous epithelium

increase of columnar epithelium and goblet cells

hemorrhage of mucosa epiderm and leukocyte migration. Tongqiao nasal drops at a high does can improve the syndrome of rat's rhinitis. Pathological changes above mentioned were greatly improved compared with the control groups.