Protective Effect of Extractum Rhodiole Roseal Co.on ExperimentalMyocardial Infarct in Dogs

Liu Jie; Qu Jibing; Qu Shaochun

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Protective Effect of Extractum Rhodiole Roseal Co.on ExperimentalMyocardial Infarct in Dogs

更新时间：2024-01-04

- Protective Effect of Extractum Rhodiole Roseal Co.on ExperimentalMyocardial Infarct in Dogs
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 3, Issue 5, Pages: 29-32(1997)
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  CLC： R256.2
- Published：1997
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Liu Jie, Qu Jibing, Qu Shaochun. Protective Effect of Extractum Rhodiole Roseal Co.on ExperimentalMyocardial Infarct in Dogs[J]. Chinese journal of experimental traditional medical formulae, 1997, 3(5): 29-32.
DOI：

Liu Jie, Qu Jibing, Qu Shaochun. Protective Effect of Extractum Rhodiole Roseal Co.on ExperimentalMyocardial Infarct in Dogs[J]. Chinese journal of experimental traditional medical formulae, 1997, 3(5): 29-32. DOI：

摘要

复方红景天浸膏（ERC），明显增加实验性心肌梗塞犬心输出量（CO）、冠脉血流量（CBF）及心肌血流量（MBF），降低冠脉阻力（CVR），降低心外膜电图（EECG）ST段抬高平均值（ST）和减少ST段显著抬高的电极数（N－ST），缩小心肌梗塞范围（MIS），降低血清肌酸磷酸激酶（CPK）及乳酸脱氢酶（LDH）活性；明显延长血栓最大凝固时间（m），减小血栓最大幅度（Ma）。

Abstract

Extractum Rhodiole roseal Co.(ERC) significantly increased the cardiac output(CO) myocardial blood flow (MBF)

decreased coronary vessel resistance

dropped the elevated level of average ST segment(ST) and the number of the leads with ST segment elevation(N-ST) of epicardial electrocardiogram(EECG)

reduced the myocardial infarct scope(MIS).ERC appeared to lower the activities of serum lactic dehydrogenase(LDH) and creatine phosphokinase(CPK) significantly.ERC also could prolong the parameter M

and shorten Ma of thrombelastogram(TEG).

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