Effect of Tongluoxifeng on the Metabolism of Cerebral Oxygenation and BloodPressure During Cerebral Ischemia-reperfusion in the Rats
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Effect of Tongluoxifeng on the Metabolism of Cerebral Oxygenation and BloodPressure During Cerebral Ischemia-reperfusion in the Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 4, Issue 1, Pages: 21-24(1998)
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CLC:R285.5
Published:1998
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Guo Gaihui, Li Ningzhang, Kaoru SAKATANI, et al. Effect of Tongluoxifeng on the Metabolism of Cerebral Oxygenation and BloodPressure During Cerebral Ischemia-reperfusion in the Rats[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(1): 21-24.
DOI:
Guo Gaihui, Li Ningzhang, Kaoru SAKATANI, et al. Effect of Tongluoxifeng on the Metabolism of Cerebral Oxygenation and BloodPressure During Cerebral Ischemia-reperfusion in the Rats[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(1): 21-24.DOI:
Effect of Tongluoxifeng on the Metabolism of Cerebral Oxygenation and BloodPressure During Cerebral Ischemia-reperfusion in the Rats
We studied the effect of Tongluoxifeng on the metabolism of cerebral oxygenation and blood pressure during cerebral ischemia-reperfusion in the rats by noninvasive near infrared spectroscopy .The results showed that oxyhaemoglobin [HB.O2] & total haemoglobin [HB.T] in the brain tissure decreased after ischemia;but deoxyhaemoglobin [HB] increased after ischemia.After reperfusion
both HB.O2& HB.T returned to the control and exceeded the control
and then decreased again.The reduction of HB.O2 & HB.T after reperfusion in normal saline group was significantly larger than that in Tongluoxifeng group.These results indicated that Tongluoxifeng could prevent the reduction of cerebral blood flow during reperfusion.
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