Study on Antimalarial Activity of Qinghaosu in Combination with Sulfa Drugs

Xue Baoyun; Ye Zuguang; Dai Baoqiang; Yang Qing; Wang Ping; Li Zelin

您当前的位置：

首页 >

文章列表页 >

Study on Antimalarial Activity of Qinghaosu in Combination with Sulfa Drugs

更新时间：2024-01-04

- Study on Antimalarial Activity of Qinghaosu in Combination with Sulfa Drugs
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 4, Issue 3, Pages: 17-19(1998)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R978.61
- Published：1998
- 稿件说明：
移动端阅览
Xue Baoyun, Ye Zuguang, Dai Baoqiang, et al. Study on Antimalarial Activity of Qinghaosu in Combination with Sulfa Drugs[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(3): 17-19.
DOI：

Xue Baoyun, Ye Zuguang, Dai Baoqiang, et al. Study on Antimalarial Activity of Qinghaosu in Combination with Sulfa Drugs[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(3): 17-19. DOI：

摘要

观察青蒿素(QHS)和磺胺类药物合并用药对伯氏鼠疟原虫抗复燃作用?结果表明

在QHS为100～400mg/kg时

QHS与磺胺嘧啶(Sulfadiazine

SD)及周效磺胺(Sulfadoxine

SDM′)合并用药能明显延缓或完全消除鼠疟原虫的复燃现象?虽然不同的磺胺药的抗疟效价并不相同

但在QHS和磺胺药剂量适当时都能延缓鼠疟原虫的复燃现象。

Abstract

The anti-recrudescent effects of Qinghaosu(QHS)in combination with sulfa drugs were studied in mice infected with Plasmodium berghei.Results showed that the combinations of QHS 100～400 mg/kg with Sulfadiazine(SD) or Sulfadoxine(SDM′) could eliminate recrudescence of Plasmodium berghei or postpone the interval between parasitemia clearance and its recrudescence. When QHS dose was increased up to 400 mg/kg

all the combinations with different sulfa drugs could delay reappearance of the parasites in the blood

although antimalarial potency of the sulfa drugs varied.

关键词

Keywords

references

Views

147

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰