Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice

Zhang Yinghua; Wu Guilan; Jiang Tingliang

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Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice

更新时间：2024-01-04

- Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 5, Issue 4, Pages: 33-36(1999)
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  CLC： R285.5
- Published：1999
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Zhang Yinghua, Wu Guilan, Jiang Tingliang. Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(4): 33-36.
DOI：

Zhang Yinghua, Wu Guilan, Jiang Tingliang. Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(4): 33-36. DOI：

摘要

当归补血汤水煎液不能刺激红系造血祖细胞(CFU-E)的增殖

而含药血清有促进CFU-E增殖的作用

随含药血清量的增加

CFU-E克隆增殖数增高

与正常对照血清有明显差别?同法取拆方与合方口饲小鼠的含药血清

观察CFU-E(3d)?BFU-E(7d)克隆增殖情况?各药促进CFU-E?BFU-E克隆增殖的平均数值顺序是黄芪血清组>归芪1∶5血清组>归芪1∶1血清组>当归血清组>空白小鼠血清组?

Abstract

Danggui Buxue Decoction did not directly stimulate reproduction of CFU-E in vitro

but the decoction-contained serum could has the effect with a obvious distinction compared with normal control serum.The quantity of CFU-E was promoted with increasing the serum dosage.The serum containing the separated formulae could stimulate reproduction of CFU-E

respectively.The proper sequence of the stimulating effect was as follows:Huang Qi>Danggui and Huang Qi(1:5)>Danggui and Huang Qi(1:1)>Danggui>normal control serum.

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Related Author

JIANG Ting-liang

WU Gui-lan

ZHANG Ying-hua

Jing YANG

Yan LEI

Yi-nan LIU

Jia-li WANG

Yan-hong HU

Related Institution

China Academy of Traditional Chinese Medicine (TCM) Medical Experimental Center, Beijing Key Laboratory of Basic Research on Prevention and Treatment of Major Diseases by TCM

Chinese Medicine Research Institute of Guangdong Pharmaceutical University, Guangdong Research Center for Integrative Medicine in Metabolic Diseases

Hainan Medical College

Wuxi Hospital of Traditional Chinese Medicine

Chengdu University of Traditional Chinese Medicine

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