Influences of Decoctions of Different places Ginseng on Cellular Immune Function in Immunosuppressed Mice
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Influences of Decoctions of Different places Ginseng on Cellular Immune Function in Immunosuppressed Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 8, Pages: 218-220(2011)
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Published:2011
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LEI Ping, GUAN Hong-quan, WANG Hao, et al. Influences of Decoctions of Different places Ginseng on Cellular Immune Function in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 218-220.
DOI:
LEI Ping, GUAN Hong-quan, WANG Hao, et al. Influences of Decoctions of Different places Ginseng on Cellular Immune Function in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 218-220.DOI:
Influences of Decoctions of Different places Ginseng on Cellular Immune Function in Immunosuppressed Mice
Objective: To compare the cellular immune function of Liaoning
Jilin and Korean ginseng in immunosuppressed mice. Method: Immunosuppressed model of mouse was induced by subcutaneous injection of hydrocortisone. Three decoctions of ginseng originated from Liaoning
Jilin and Korea were ig given to explore CD3
CD4
CD8 in spleen cell suspension by flow cytometry. Serum IFN-γ level was determined by ELISA assay;and SRBC was used to induce delayed-type hypersensitivity (DTH). Result: The CD3
CD4 and CD8 of spleen cell suspension were increased after each ginseng decoction treatment
Korean ginseng could increase the CD4 and CD4/CD8 ratio for the immunosuppressed mice significantly(P<0.05). Liaoning ginseng had no significant difference compared with that of Jilin ginseng or Korean ginseng. The levels of DTH and IFN-γwere also raised significantly after each decoction treatment(P<0.05)
and Liaoning ginseng had no significant difference compared with that of Jilin ginseng or Korean ginseng. Conclusion: Liaoning ginseng decoction can improve cellular immune function on immunosuppressed mice
and Liaoning ginseng had no significant difference compared with Jilin and Korean ginseng.