Efficacy of Yiqi Huoxue Fang Combined with Ketamine Spinal Block on Treating Intractable Postherpetic Neuralgia

FENG Hai-jun

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Efficacy of Yiqi Huoxue Fang Combined with Ketamine Spinal Block on Treating Intractable Postherpetic Neuralgia

更新时间：2024-01-04

- Efficacy of Yiqi Huoxue Fang Combined with Ketamine Spinal Block on Treating Intractable Postherpetic Neuralgia
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 6, Pages: 320-322(2013)
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- Published：2013
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FENG Hai-jun. Efficacy of Yiqi Huoxue Fang Combined with Ketamine Spinal Block on Treating Intractable Postherpetic Neuralgia[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 320-322.
DOI：

FENG Hai-jun. Efficacy of Yiqi Huoxue Fang Combined with Ketamine Spinal Block on Treating Intractable Postherpetic Neuralgia[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 320-322. DOI：

摘要

目的: 观察益气活血方联合氯胺酮椎管内阻滞治疗顽固性带状疱疹后遗神经痛(PHN)的临床疗效。方法: 110例带状疱疹后遗神经痛患者(PHN)随机分为对照组54例和治疗组56例。对照组单用氯胺酮椎管内阻滞治疗

1次/周

共8次。治疗组在此基础上加用益气活血方内服治疗

1剂/d

常规水煎分2次服用。两组在必要时加用曲马多止痛。疗程8周。结果: 治疗7 d

4周及8周

治疗组VAS评分低于对照组(P<0.01);治疗组疗效明显优于对照组(P<0.01);治疗后4周

8周治疗组QOL评分高于对照组(P<0.01);治疗组平均曲马多片总量为(230.5±72.4)mg

低于对照组的(725.7±581.9)mg(P<0.01)。结论: 益气活血方联合氯胺酮椎管内阻滞治疗顽固性带状疱疹后遗神经痛安全性有效

值得临床推广。

Abstract

Objective: To observe the curative effect of Yiqi Huoxue Fang (YHF) combined with ketamine anesthesia in vertebral canal on treating intractable postherpetic neuralgia(PHN). Method: One hundred and ten cases of PHN were randomly divided into control group (n=54) and treatment group (n=56).All patients were given ketamine spinal block therapy once a week for a total of eight times.The treatment group on this basis was received YHF once daily(given by half dose

bid).The patients in two groups were given multi-analgesic tramadol when necessary during the investigation of 8 weeks. Result: After treatment for 7 days

4 weeks and 8 weeks

the Visual analogue scale(VAS) scores of the treatment group were lower than those in the control group(P<0.01); the efficacy in the treatment group was significantly better than the control group(P<0.01).The quality of life(QOL) scores in the treatment group after treatment of 4 weeks and 8 weeks were higher than those in the control group (P<0.01); and the consumed tramadol in the treatment group was (230.5±72.4)mg

which is lower than that in the control group (725.7±581.9)mg (P<0.01). Conclusion: YHF combined with ketamine spinal block is effective and safe in the treatment of intractable PHN.

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