Effect of Jiangzhi Jianfei Capsule on 50 Patients of Metabolic Syndrome

YANG Li; XU Jing-wen; YANG Shu-guo; LIU Zai-song; ZHENG Yang; JIAO Dong-hai

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Effect of Jiangzhi Jianfei Capsule on 50 Patients of Metabolic Syndrome

更新时间：2024-09-23

- Effect of Jiangzhi Jianfei Capsule on 50 Patients of Metabolic Syndrome
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 5, Pages: 300-303(2013)
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- Published：2013
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YANG Li, XU Jing-wen, YANG Shu-guo, et al. Effect of Jiangzhi Jianfei Capsule on 50 Patients of Metabolic Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 300-303.
DOI：

YANG Li, XU Jing-wen, YANG Shu-guo, et al. Effect of Jiangzhi Jianfei Capsule on 50 Patients of Metabolic Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 300-303. DOI：

摘要

目的: 观察服用降脂减肥胶囊(大黄提取粉末等)加辨证中药汤剂配合腹部推摩治疗代谢综合征(MS)的疗效。方法: 50例MS用辨证中药汤剂送服降脂减肥胶囊配合循经推摩治疗

疗程为1个月

观察对MS的疗效。结果: 50例MS住院治疗1个月后对减肥全部有效

其显效率达82.9%

平均1个月减体重9.32 kg(相当于减去原体重的8.32%)

腹围缩小11.86 cm(相当于减去原腹围的9.5%)

减去体脂4.11 kg(相当于减去原体脂的10.2%)

减水分2.28 kg(相当于减去多余水分的47%)

体重指数(BMI)下降3.52。50例中43例高血压患者经1个月治疗后全部有效

其中37例降至正常(86.0%)

24例血糖升高患者

18例降至正常水平(75%)

1例无效(4%)

50例中高血脂症42例有效36例

有效率为85.7%

其中16例降至正常(44%)

4种类型的MS中对合并高血压的降压疗效最佳

但减体重最差。此前的动物实验与27例临床研究证明大黄提取粉不仅具有较好的减肥作用

同时能降低瘦素

改善机体胰岛素的抵抗状况

此作用与血清肿瘤坏死因子-α(TNF-α)浓度降低有关。结论: 目前全世界尚缺乏一种有效的防治MS药物

因此如何在祖国医药中寻找出一种能防治MS的中药是研究的主要方向之一。

Abstract

Objective:To study effect of the Jiangzhi Jianfei Capsule on 50 cases of metabolic syndrome. Method: Fifty metabolic syndrom were recruited according to the national health organisis criteria. Each patient was administrated with refiined rhubarb powder 2-6 capsules bid for 4 weeks. Routin clinical assays: serum glucose

lipids

liver function and blood pressure were massured. Result and Conclusion: The capsule of powder extracted from rhubarb reduced the body weight

triglyceride

serum aspartate aminotrans ferase(AST)

alanine transaminase(ALT) uric acid and blood pressure were effective on the metabol 50 patients suffering from metabolic syndrome.The same time

the level of insulin

peptide C and tumor necrosis factor-α(TNF-α) remarkably lowered. There was a positive relationship between the serum insulin and TNF-α level.

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Related Author

YANG Li

XU Jing-wen

YANG Shu-guo

LIU Zai-song

ZHENG Yang

JIAO Dong-hai

HAN Yi

HAN Yubo

Related Institution

Beijing Weiren Chinese Traidional Hospital Losing-Weight Department

Heilongjiang University of Chinese Medicine

First Affiliated Hospital of Heilongjiang University of Chinese Medicine

Hunan University of Chinese Medicine

Hunan Brain Hospital （The Second People's Hospital of Hunan Province）

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