-Glucosidase Inhibitory Activity of

YANG Bao-cheng; PENG Tao; HUANG Zhong-bi; ZHANG Qian-jun; KANG Wen-yi

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-Glucosidase Inhibitory Activity of

更新时间：2024-01-04

- -Glucosidase Inhibitory Activity of
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 6, Pages: 103-105(2013)
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- Published：2013
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YANG Bao-cheng, PENG Tao, HUANG Zhong-bi, et al. -Glucosidase Inhibitory Activity of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 103-105.
DOI：

YANG Bao-cheng, PENG Tao, HUANG Zhong-bi, et al. -Glucosidase Inhibitory Activity of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 103-105. DOI：

摘要

目的: 对疏花假地豆体外抗氧化活性进行研究。方法: 采用清除二苯代苦味酰基(DPPH)自由基、清除(ABTS)自由基及铁离子还原/抗氧化能力(FRAP)测定法

评价疏花假地豆体外抗氧化活性

并与阳性对照二丁基羟基甲苯(BHT)比较。结果: 疏花假地豆体外抗氧化活性较好。其中乙酸乙酯提取部位清除DPPH自由基(IC50=35.66 mg·L-1)、ABTS自由基(IC50=8.49 mg·L-1)及还原Fe3+的能力(TEAC=756.20 μmol·g-1)较好

但仍低于阳性对照BHT(IC50=3.69 mg·L-1

IC50=6.64 mg·L-1和TEAC=4 997.76 μmol·g-1)。结论: 疏花假地豆乙酸乙酯提取部位体外抗氧化活性相对于其他部位最好。

Abstract

Objective: To evaluate antioxidant activity of Desmodium heterocarpon in vitro. Method: 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging

diamonium salt (ABTS) radical scavenging and ferric reducing antioxidant power (FRAP) assay were used to evaluated D.heterocarpon with BHT as positive control. Result: Antioxidant activity of D.heterocarpon was good.Ethyl acetate extract of D.heterocarpon showed the DPPH radical scavenging (IC50=35.66 mg·L-1)

ABTS radical scavenging (IC50=8.49 mg·L-1)

and ferric reducing antioxidant power (TEAC=756.20 μmol·g-1) and those were higher than that of other extracts.But it was still inferior to positive control BHT (IC50=3.69 mg·L-1

IC50=6.64 mg·L-1 and TEAC=4 997.76 μmol·g-1

respectively). Conclusion: Ethyl acetate extract showed the best antioxidant activity in three extracts.

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Related Institution

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Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine， Henan University of Chinese Medicine

School of Pharmaceutical Sciences，Key Laboratory of TCM Active Ingredient，Ministry of Education，Changchun University of Chinese Medicine

School of Pharmacy， Chengdu University of Traditional Chinese Medicine（TCM）

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines， Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

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