Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ
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Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ
Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 5, Pages: 158-160(2013)
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Published:2013
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LIU Shuai, LI Fei, HOU Yue-fei, et al. Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 158-160.
DOI:
LIU Shuai, LI Fei, HOU Yue-fei, et al. Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 158-160.DOI:
Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ
Objective:To explore the influence of tannins from Chebulae Fructus on aconitum alkaloids of Aconitum processed with Chebulae Fructus
and analyze the mechanism of how Chebulae Fructus effect on Aconitum kusnezoffii by process. Method: Processing Aconiti Kusnezoffii Ratix with Chebulae Fructus decoctions
pure water and Chebulae Fructus decoctions without tannins. Detecting the concentration of aconitine
hypaconitine
mesaconitine
benzoyl aconine
benzoyl hypaconitine and benzoyl mesaconitine by using HPLC method. Result: The concentration of biester-type aconitum alkaloids: processed with Chebulae Fructus decoctions>processed with pure water>processed with Chebulae Fructus decoctions without tannins. The concentration of monoester-type aconitum alkaloids: processed with Chebulae Fructus decoctions>processed with Chebulae Fructus decoctions without tannins>processed with pure water. Conclusion: Tannins can inhibit alkaloids dissolved out and make it slow to hydrolysis so that reduce the toxic effects.
Influence of Tannins from Chebulae Fructus on Aconitum Alkaloids of Aconitum kusnezoffii Processed with Chebulae Fructus-Principal of Aconitum Processed with Chebulae FructusⅠ
Comparision of Contents of Aconitum Alkaloids between the Decoctions of Aconitum Processed with Myrobalan and Co-decoctions of Aconitum and Myrobalan——Principal of Aconitum Processed with MyrobalanⅡ
Herbal Textual Research on Chebulae Fructus in Famous Classical Formulas
Detoxification Mechanism of Combined Chebulae Fructus, Glycyrrhizae Radix et Rhizoma and Prepared Aconiti Kusnezoffii Radix Cocta in Regulating Cardiac Metabolic Enzyme CYP2J3
Analysis of Chemical Components in Supernatant and Precipitate of Sanajon Oral Liquid Based on UPLC-Q-TOF-MSE Technology
Related Author
LIU Shuai
LI Fei
HOU Yue-fei
YANG Chang
TAN Peng
LI Xiang-ri
DU Hong
Aruhan
Related Institution
Beijing University of Chinese Medicine
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences
Inner Mongolia Traditional Chinese and Mongolian Medical Research Institute
Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine
Institute of Medicinal Plant,Yunnan Academy of Agricultural Sciences