Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 6, Pages: 359-362(2013)
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Published:2013
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JIANG Xiao, LI Sha-sha, Zhang Bin, et al. Progress on Proniosomes as Drug Carriers[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 359-362.
DOI:
JIANG Xiao, LI Sha-sha, Zhang Bin, et al. Progress on Proniosomes as Drug Carriers[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(6): 359-362.DOI:
Refer to the related literature in recent 10 years
the properties
the preparation
drug entrapment
and the applications of the proniosmes were reviewed in this paper. The characters are gel and a dry free-flowing granular.Preparation methods are mainly slurry method
coacervation phase separation method and slow spray-coating method.Factors the drug entrapment rate are the type and content of surfactant
cholesterol and lecithin content and the pH of the hydration medium.Applied to difficult soluble drugs
nsaids
hormone drugs
antihypertensive drug
anti-inflammatory analgesic
cerebrovascular expansion medicine
antiallergic
etc. But the former research of pronisomes are mainly pauses in the laboratory stage
the mechanism of action and clinical treatment need further exploration.
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