Influence of Zexie Danming Drink on Serum Lipids and Adiponectin in Rats with Hyperlipidemia
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Influence of Zexie Danming Drink on Serum Lipids and Adiponectin in Rats with Hyperlipidemia
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 24, Pages: 300-303(2012)
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Published:2012
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HONG Jun, ZHAO Ming-fen, WANG Jian-ping, et al. Influence of Zexie Danming Drink on Serum Lipids and Adiponectin in Rats with Hyperlipidemia[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 300-303.
DOI:
HONG Jun, ZHAO Ming-fen, WANG Jian-ping, et al. Influence of Zexie Danming Drink on Serum Lipids and Adiponectin in Rats with Hyperlipidemia[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 300-303.DOI:
Influence of Zexie Danming Drink on Serum Lipids and Adiponectin in Rats with Hyperlipidemia
Objective:To observe the influence of Zexie Danming Drink (ZDD) on serum lipids and adiponectin in hyperlipidemic rats. Method: A high-fat diet was fed 14 d to establish rat model of hyperlipidemia. Rats in different groups were given drugs accordingly for 21 days: ZDD high dose (4.0 g·kg-1)
and adiponectin factors (ADP) and liver pathological changes were determined and observed. Result: Compared with model group
TC and TG in ZDD high dose group were significantly lowered (P<0.01)
LDL-C decreased significantly (P<0.05)
serum ADP level increased significantly l (P<0.01) and with a trend of elevation in HDL-C
. Compared with model group
in the middle dose group serum ADP levelwas significantly increased. Conclusion: ZDD of high dose or medium dose can regulate blood lipids and adiponectin levels
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