Compatible Stability Studies on Danshen Dripping Solution and Cefoxintin Sodium for Injection
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Compatible Stability Studies on Danshen Dripping Solution and Cefoxintin Sodium for Injection
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 23, Pages: 120-122(2012)
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Published:2012
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ZHANG Hong-feng, CHEN Chen, LIU Yan-juan, et al. Compatible Stability Studies on Danshen Dripping Solution and Cefoxintin Sodium for Injection[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 120-122.
DOI:
ZHANG Hong-feng, CHEN Chen, LIU Yan-juan, et al. Compatible Stability Studies on Danshen Dripping Solution and Cefoxintin Sodium for Injection[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 120-122.DOI:
Compatible Stability Studies on Danshen Dripping Solution and Cefoxintin Sodium for Injection
Objective: To investigate the compatible stability of danshen dripping solution and cefoxintin sodium. Method: The content of sodium danshensu
protocatechualdehyde and cefoxintin were determined after compatibility of danshen dripping solution and cefoxintin sodium within 4 hours by HPLC
and the changes of solution color
pH value and insoluble particles were observed in the simulation conditions of clinical concentration. Result: The solution color and pH value showed no obvious changes. The number of insoluble particles was increased and the content of sodium danshensu
protocatechualdehyde and cefoxintin were reduced with the extending of compatible time. Conclusion: The solution was unstable after compatibility of danshen dripping solution and cefoxintin sodium within 4 hours
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