Objective: To establish a HPLC-FP analysis method for identification of drying and sulphur fumigated Lonicera japonica to comparison the impact on the internal components of sulphur fumigated Lonicera japonica. Method: The HPLC separation was performed on AichromBond-AQ C18 (4.6 mm×250 mm

5 μm) by gradient elution with a mixture consisting of acetonitrile-0.1% phosphate acid; the flow rate was 1.0 mL·min-1; the column temperature was kept at 30℃; the detective wavelength was 238 nm. Result: Twenty common peaks were obtained in 10 batches of samples and 16 common peaks were obtained in 10 batches of samples. The similarity of each fingerprint within one group was higher than 0.96 in drying L. japonica and 0.90 in sulphur fumigated L. japonica. Conclusion: This method shows high precision

good repeatability. It can be used for assessment the quality of drying and sulphur fumigated L. japonica.